SETDB1 anticorps (SET Domain, Bifurcated 1)

Details for Product anti-SETDB1 Antibody No. ABIN967016, Fournisseur: Connectez-vous pour afficher
Antigène
  • SETDB1
  • NV10069
  • fc07d03
  • si:ch211-81a5.6
  • wu:fc07d03
  • ESET
  • H3-K9-HMTase4
  • KG1T
  • KMT1E
  • TDRD21
  • AU022152
  • mKIAA0067
  • SET domain, bifurcated 1
  • myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11
  • SET domain bifurcated 1
  • histone-lysine N-methyltransferase SETDB1
  • SET domain, bifurcated 1a
  • SET domain bifurcated 1 L homeolog
  • Setdb1
  • MLLT11
  • SETDB1
  • LOC100120014
  • LOC100461671
  • setdb1a
  • setdb1.L
Reactivité
Humain, Singe, Souris
110
50
28
13
2
1
1
1
1
1
Hôte
Souris
82
29
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp SETDB1 est non-conjugé
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
97
56
29
13
13
13
11
5
5
3
2
1
1
1
1
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène Purified recombinant fragment of human SETDB1 expressed in E. Coli.
Clone 5H6D4
Isotype IgG1
Purification Ascitic fluid
Plasmids, Primers & others Plasmids, Primers & others SETDB1 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation SETDB1 (SETDB1 Antibody Extrait)
Sujet This gene encodes a histone methyltransferase. The encoded enzyme catalyzes the reaction of S-adenosyl-Lmethionine and histone L-lysine to produce S-adenosyl-L-homocysteine and histone N(6)-methyl-L-lysine. The encoded protein likely functions in transcriptional repression.
Tissue specificity: Widely expressed. High expression in testis.
Synonyms: ESET, KG1T, KMT1E, KIAA0067, H3-K9-HMTase4, SETDB1
Poids moléculaire 180kDa
ID gène 9869
Indications d'application Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C
Produit citée dans: Gao, Yu, Bi, Jiang, Cui, Sun, Ma: "Akt/PKB interacts with the histone H3 methyltransferase SETDB1 and coordinates to silence gene expression." dans: Molecular and cellular biochemistry, Vol. 305, Issue 1-2, pp. 35-44, 2007 (PubMed).

Background publications Rosendorff, Sakakibara, Lu, Kieff, Xuan, DiBacco, Shi, Shi, Gill: "NXP-2 association with SUMO-2 depends on lysines required for transcriptional repression." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 14, pp. 5308-13, 2006 (PubMed).

Gevaert, Staes, Van Damme, De Groot, Hugelier, Demol, Martens, Goethals, Vandekerckhove: "Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC." dans: Proteomics, Vol. 5, Issue 14, pp. 3589-99, 2005 (PubMed).

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