Tec Protein Tyrosine Kinase (TEC) anticorps

N° du produit ABIN967165

Cet anticorps Souris Monoclonal détecte spécifiquement Tec Protein Tyrosine Kinase dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.Il a été cité dans 1 publication.

Aperçu rapide pour Tec Protein Tyrosine Kinase (TEC) anticorps (ABIN967165)

Antigène: Tec Protein Tyrosine Kinase (TEC)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), ELISA

Clone: 3A5

Détail du produit

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of TEC expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Référence

Yang, Ghiotto, Barbarat, Olive: "The role of Tec protein-tyrosine kinase in T cell signaling." dans: The Journal of biological chemistry, Vol. 274, Issue 2, pp. 607-17, (1999) (PubMed).

Détail du antigène

Antigène: Tec Protein Tyrosine Kinase (TEC)

Autre désignation: TEC

Sujet: TEC, it belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
Synonyms: PSCTK4

Poids moléculaire: 74kDa

ID gène: 7006

Pathways: Fc-epsilon Receptor Signaling Pathway