TLR9 anticorps (N-Term)

N° du produit ABIN967190

Il existe 4+ publications pour ce produit. L’anticorps anti-TLR9 Polyclonal Lapin est utilisé pour la détection de TLR9 dans des échantillons de Souris. Il a été validé pour IHC.

Aperçu rapide pour TLR9 anticorps (N-Term) (ABIN967190)

Antigène: TLR9 (Toll-Like Receptor 9 (TLR9))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR9 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-TLR9 anticorps

Épitope: N-Term

Immunogène: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of mouse Tlr9 (Toll-like receptor 9)

Information d'application

Restrictions: For Research Use only

Stockage

Stock: 4 °C

Références pour anticorps anti-TLR9 (ABIN967190)

Kiyokawa, Akashi-Takamura, Shibata, Matsumoto, Nishitani, Kuroki, Seto, Miyake: "A single base mutation in the PRAT4A gene reveals differential interaction of PRAT4A with Toll-like receptors." dans: International immunology, Vol. 20, Issue 11, pp. 1407-15, (2008) (PubMed).

Tabeta, Georgel, Janssen, Du, Hoebe, Crozat, Mudd, Shamel, Sovath, Goode, Alexopoulou, Flavell, Beutler: "Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 10, pp. 3516-21, (2004) (PubMed).

Chuang, Lee, Kline, Mathison, Ulevitch: "Toll-like receptor 9 mediates CpG-DNA signaling." dans: Journal of leukocyte biology, Vol. 71, Issue 3, pp. 538-44, (2002) (PubMed).

Bauer, Kirschning, Häcker, Redecke, Hausmann, Akira, Wagner, Lipford: "Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 16, pp. 9237-42, (2001) (PubMed).

Détails sur TLR9

Antigène: TLR9 (Toll-Like Receptor 9 (TLR9))

Autre désignation: Tlr9

Sujet: Tlr9 (Toll-like receptor 9) participates in the innate immune response to microbial agents. Tlr9 (Toll-like receptor 9) detects the unmethylated cytidine-phosphate-guanosine (CpG) motifs present in bacterial DNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Tlr9 (Toll-like receptor 9) plays a role in defense against sytemic mouse cytomegalovirus infection. Tlr9 (Toll-like receptor 9) binds MYD88 via their respective TIR domains and interacts with CNPY3. Tlr9 (Toll-like receptor 9) belongs to the Toll-like receptor family and contains 26 LRR (leucine-rich) repeats and 1 TIR domain.

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades