Integrin beta 3 anticorps

N° du produit ABIN967485

Cet anticorps anti-Integrin beta 3 est un anticorps Souris Monoclonal détectant Integrin beta 3 dans WB, FACS et IHC (fro). Adapté pour Humain, Boeuf (Vache), Babouin, Cynomolgus et Macaque rhésus. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour Integrin beta 3 anticorps (ABIN967485)

Antigène: Integrin beta 3 (ITGB3)

Reactivité: Humain, Boeuf (Vache), Babouin, Cynomolgus, Macaque rhésus

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin beta 3 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: VI-PL2

Détail du produit anti-Integrin beta 3 anticorps

Marque: BD Pharmingen™

Attributs du produit: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG1 kappa

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4° C.

Références pour anticorps anti-Integrin beta 3 (ABIN967485)

Mason, André, Bensussan, Buckley, Civin, Clark, de Haas, Goyert, Hadam, Hart, Horejsí, Meuer, Morissey, Schwartz-Albiez, Shaw, Simmons, Uguccioni, van der Schoot, Viver, Zola: "CD antigens 2001." dans: Tissue antigens, Vol. 58, Issue 6, pp. 425-30, (2002) (PubMed).

Détails sur Integrin beta 3

Antigène: Integrin beta 3 (ITGB3)

Autre désignation: CD61

Sujet: Reacts with integrin beta3, a 105 kDa transmembrane glycoprotein, expressed on platelets, megakaryocytes, osteoclasts and endothelia. Integrin beta3 associates with gpIIa (CD41) to form the CD41/CD61 complex which mediates platelet adhesion and aggregation. CD61 also associates with CD51 to form the CD51/CD61 complex (vitronectin receptor). CD61 appears to bind to fibrinogen, fibronectin, vWF, vitronectin, and thrombospondin to mediate cell adhesion. This antibody is routinely tested by flow cytometric analysis.
Synonyms: Integrin beta3 Chain

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex