Syntaxin 6 anticorps (AA 6-136)

N° du produit ABIN968080

Cet anticorps Souris Monoclonal détecte spécifiquement Syntaxin 6 dans WB, IHC, IF et IP. Il présente une réactivité envers Humain, Poulet, Souris, Rat, Chien et Grenouille et a été mentionné dans 4+ publications.

Aperçu rapide pour Syntaxin 6 anticorps (AA 6-136) (ABIN968080)

Antigène: Syntaxin 6 (STX6)

Reactivité: Humain, Poulet, Souris, Rat, Chien, Grenouille

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Syntaxin 6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: 30-Syntaxin 6

Détail du produit anti-Syntaxin 6 anticorps

Épitope: AA 6-136

Réactivité croisée: Humain, Souris, Chien, Poulet, Grenouille

Attributs du produit: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Rat Syntaxin 6 aa. 6-136

Isotype: IgG1

Information d'application

Commentaires:

Related Products: ABIN968533, ABIN967389

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store undiluted at -20°C.

Références pour anticorps anti-Syntaxin 6 (ABIN968080)

Shewan, van Dam, Martin, Luen, Hong, Bryant, James: "GLUT4 recycles via a trans-Golgi network (TGN) subdomain enriched in Syntaxins 6 and 16 but not TGN38: involvement of an acidic targeting motif." dans: Molecular biology of the cell, Vol. 14, Issue 3, pp. 973-86, (2003) (PubMed).

Mullock, Smith, Ihrke, Bright, Lindsay, Parkinson, Brooks, Parton, James, Luzio, Piper: "Syntaxin 7 is localized to late endosome compartments, associates with Vamp 8, and Is required for late endosome-lysosome fusion." dans: Molecular biology of the cell, Vol. 11, Issue 9, pp. 3137-53, (2000) (PubMed).

Ramalho-Santos, Moreno, Sutovsky, Chan, Hewitson, Wessel, Simerly, Schatten: "SNAREs in mammalian sperm: possible implications for fertilization." dans: Developmental biology, Vol. 223, Issue 1, pp. 54-69, (2000) (PubMed).

Bock, Lin, Scheller: "A new syntaxin family member implicated in targeting of intracellular transport vesicles." dans: The Journal of biological chemistry, Vol. 271, Issue 30, pp. 17961-5, (1996) (PubMed).

Détails sur Syntaxin 6

Antigène: Syntaxin 6 (STX6)

Autre désignation: Syntaxin 6

Sujet: Signal transmission between cells is often regulated by the secretion of neurotransmitters or hormones into the extracellular space. This process is controlled by a complex pathway of membrane trafficking which leads to membrane fusion and secretion. Syntaxin 1 is involved in three important complexes that modulate the secretion process: syntaxin and n-sec-1, syntaxin, VAMP, and SNAP-25, and syntaxin, VAMP, SNAP-25, alphaSNAP, and NSF (20S complex). Syntaxin 6 is a 255 amino acid member of the syntaxin family. It contains a C-terminal transmembrane domain and is located at the Golgi apparatus. In addition, Syntaxin 6 displays significant (47% identity) homology with SNAP-25. In vitro, Syntaxin 6 has been reported to interact with alpha-SNAP. Syntaxin 6 has been reported to have a calculated molecular weight of 30.6 kDa, but has been observed to migrate in a range inbetween ~ 31-35 kDa.

Poids moléculaire: 31-35 kDa

Pathways: Synaptic Vesicle Exocytosis