RAB11A anticorps (AA 86-207)

N° du produit ABIN968091

Cet anticorps anti-RAB11A est un anticorps Souris Monoclonal détectant RAB11A dans WB, IHC et IP. Adapté pour Humain, Souris, Rat, Chien et Poulet. Ce Primary Antibody a été cité dans 5+ publications.

Aperçu rapide pour RAB11A anticorps (AA 86-207) (ABIN968091)

Antigène: RAB11A (RAB11A, Member RAS Oncogene Family (RAB11A))

Reactivité: Humain, Souris, Rat, Chien, Poulet

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RAB11A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: 47-Rab11

Détail du produit anti-RAB11A anticorps

Épitope: AA 86-207

Réactivité croisée: Chien, Poulet, Souris, Rat (Rattus)

Attributs du produit: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Human Rab11 aa. 86-207

Isotype: IgG2a

Information d'application

Commentaires:

Related Products: ABIN968619, ABIN967389

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store undiluted at -20°C.

Références pour anticorps anti-RAB11A (ABIN968091)

Steiner, Sarria, Glauser, Magnin, Catsicas, Hirling: "Modulation of receptor cycling by neuron-enriched endosomal protein of 21 kD." dans: The Journal of cell biology, Vol. 157, Issue 7, pp. 1197-209, (2002) (PubMed).

Choudhury, Dominguez, Puri, Sharma, Narita, Wheatley, Marks, Pagano: "Rab proteins mediate Golgi transport of caveola-internalized glycosphingolipids and correct lipid trafficking in Niemann-Pick C cells." dans: The Journal of clinical investigation, Vol. 109, Issue 12, pp. 1541-50, (2002) (PubMed).

Woods, Roberts, Choudhary, Barry, Mazaki, Sabe, Morley, Critchley, Norman: "Paxillin associates with poly(A)-binding protein 1 at the dense endoplasmic reticulum and the leading edge of migrating cells." dans: The Journal of biological chemistry, Vol. 277, Issue 8, pp. 6428-37, (2002) (PubMed).

Lai, Stubbs, Artzt: "Molecular analysis of mouse Rab11b: a new type of mammalian YPT/Rab protein." dans: Genomics, Vol. 22, Issue 3, pp. 610-6, (1995) (PubMed).

Sakurada, Uchida, Yamaguchi, Aisaka, Ito, Ohmori, Takeyama, Ueda, Hori, Ohyanagi: "Molecular cloning and characterization of a ras p21-like GTP-binding protein (24KG) from rat liver." dans: Biochemical and biophysical research communications, Vol. 177, Issue 3, pp. 1224-32, (1991) (PubMed).

Détails sur RAB11A

Antigène: RAB11A (RAB11A, Member RAS Oncogene Family (RAB11A))

Autre désignation: Rab11

Sujet: The Rab proteins are small GTP-binding molecules that are localized to specific intracellular vesicles and organelles. It has been proposed that Rab proteins cycle between GTP- and GDP-bound forms and that this is related to their function as regulators of vesicular traffic. The Rab11 gene encodes a 24 kDa protein of 214 amino acids that has been detected in liver, brain, testis, spleen, and heart. Rab11 protein was isolated from the golgi-microsomal fraction of rat liver and has been detected in the Trans-golgi Network, secretory vesicles, and the pericentriolar recycling endosomes. The distribution of Rab11 indicates that this small protein is involved in regulating traffic at the Golgi complex.

Poids moléculaire: 24 kDa

Pathways: Regulation of Cell Size, Thromboxane A2 Receptor Signaling, Regulation of long-term Neuronal Synaptic Plasticity