GOLGA5 anticorps (AA 510-713)

N° du produit ABIN968506

Cet anticorps Souris Monoclonal détecte spécifiquement GOLGA5 dans WB et IF. Il présente une réactivité envers Humain et Chien et a été mentionné dans 1 publication.

Aperçu rapide pour GOLGA5 anticorps (AA 510-713) (ABIN968506)

Antigène: GOLGA5 (Golgin A5 (GOLGA5))

Reactivité: Humain, Chien

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GOLGA5 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 26-Golgin

Détail du produit anti-GOLGA5 anticorps

Épitope: AA 510-713

Réactivité croisée: Chien

Attributs du produit: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Human Golgin-84 aa. 510-713

Isotype: IgG1

Information d'application

Commentaires:

Related Products: ABIN968552, ABIN967389

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store undiluted at -20° C.

Références pour anticorps anti-GOLGA5 (ABIN968506)

Bascom, Srinivasan, Nussbaum: "Identification and characterization of golgin-84, a novel Golgi integral membrane protein with a cytoplasmic coiled-coil domain." dans: The Journal of biological chemistry, Vol. 274, Issue 5, pp. 2953-62, (1999) (PubMed).

Détails sur GOLGA5

Antigène: GOLGA5 (Golgin A5 (GOLGA5))

Autre désignation: Golgin-84

Sujet: The Golgi apparatus is a complex and dynamic organelle that functions in protein sorting and modification. Numerous structural and regulatory proteins are involved in the budding, docking, and fusion of Golgi-directed vesicles. Golgin-84 is an integral membrane protein associated with the Golgi. Sequence analysis of the C-terminal region of Golgin-84 demonstrates a 14 residue region extending into the lumen of the Golgi, a membrane insertion sequence, and a Golgi retention signal. The large N-terminal cytoplasmic region contains a coiled-coil domain that is required for dimerization and two leucine zipper domains. Golgin-84 is ubiquitously expressed, but is abundant in testis. Golgin-84 has sequence homology to coiled-coil containing myosin family members and to several other Golgi proteins, including trans-Golgi p230 and gigantin. Trans-Golgi p230 has been implicated in the biogenesis of specific Golgi vesicles, while gigantin is implicated in the tethering of non-clathrin coated vesicles and in the anchoring of adjacent Golgi cisternae. Thus, Golgin-84 may have similar roles in vesicle biogenesis, docking, and fusion at the Golgi interface.

Poids moléculaire: 84 kDa