Smooth Muscle Actin anticorps

N° du produit ABIN968947

Cet anticorps Souris Monoclonal détecte spécifiquement Smooth Muscle Actin dans WB, IHC, FACS, ELISA et ICC. Il présente une réactivité envers Humain, Rat, Souris et Singe et a été mentionné dans 2+ publications.

Aperçu rapide pour Smooth Muscle Actin anticorps (ABIN968947)

Antigène: Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

Reactivité: Humain, Rat, Souris, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Smooth Muscle Actin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)

Clone: 4A4

Détail du produit anti-Smooth Muscle Actin anticorps

Fonction: ACTA2 Antibody

Purification: Ascitic fluid

Immunogène: Synthesized peptide of human ACTA2.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Smooth Muscle Actin (ABIN968947)

Shimojima, Yamamoto: "ACTA2 is not a major disease-causing gene for moyamoya disease." dans: Journal of human genetics, Vol. 54, Issue 11, pp. 687-8, (2009) (PubMed).

Morisaki, Akutsu, Ogino, Kondo, Yamanaka, Tsutsumi, Yoshimuta, Okajima, Matsuda, Minatoya, Sasaki, Tanaka, Ishibashi-Ueda, Morisaki: "Mutation of ACTA2 gene as an important cause of familial and nonfamilial nonsyndromatic thoracic aortic aneurysm and/or dissection (TAAD)." dans: Human mutation, Vol. 30, Issue 10, pp. 1406-11, (2009) (PubMed).

Détails sur Smooth Muscle Actin

Antigène: Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

Autre désignation: ACTA2

Sujet: The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Poids moléculaire: 42 kDa

ID gène: 59

UniProt: P62736

Pathways: Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development