APOB anticorps
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- Antigène Voir toutes APOB Anticorps
- APOB (Apolipoprotein B (APOB))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp APOB est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Purification
- purified
- Immunogène
- Purified recombinant fragment of human ApoB expressed in E. coli.
- Clone
- 6G6
- Isotype
- IgG1
- Top Product
- Discover our top product APOB Anticorps primaire
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- Indications d'application
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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Apolipoprotein B levels, APOB alleles, and risk of ischemic cardiovascular disease in the general population, a review." dans: Atherosclerosis, Vol. 206, Issue 1, pp. 17-30, (2009) (PubMed).
: "Apolipoprotein B Is an innate barrier against invasive Staphylococcus aureus infection." dans: Cell host & microbe, Vol. 4, Issue 6, pp. 555-66, (2008) (PubMed).
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Apolipoprotein B levels, APOB alleles, and risk of ischemic cardiovascular disease in the general population, a review." dans: Atherosclerosis, Vol. 206, Issue 1, pp. 17-30, (2009) (PubMed).
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- Antigène
- APOB (Apolipoprotein B (APOB))
- Autre désignation
- ApoB (APOB Produits)
- Synonymes
- anticorps FLDB, anticorps LDLCQ4, anticorps Ac1-060, anticorps Apo B-100, anticorps ApoB-100, anticorps ApoB-48, anticorps AI315052, anticorps apob-100, anticorps apob-48, anticorps APOB-100, anticorps ApoB(100), anticorps APOB, anticorps apolipoprotein B, anticorps APOB, anticorps Apob
- Sujet
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Description: This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.
Aliases: FLDB, LDLCQ4
- Poids moléculaire
- 516 kDa
- ID gène
- 338
- HGNC
- 338
- Pathways
- Lipid Metabolism
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