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BLK anticorps

BLK Reactivité: Humain ELISA, IHC Hôte: Souris Monoclonal 9D10D1 unconjugated
N° du produit ABIN968980
  • Antigène Voir toutes BLK Anticorps
    BLK (B Lymphoid Tyrosine Kinase (BLK))
    Reactivité
    • 65
    • 23
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 53
    • 9
    • 1
    Souris
    Clonalité
    • 55
    • 10
    Monoclonal
    Conjugué
    • 34
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BLK est non-conjugé
    Application
    • 52
    • 36
    • 27
    • 13
    • 13
    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of BLK expressed in E. coli.
    Clone
    9D10D1
    Isotype
    IgG2a
    Top Product
    Discover our top product BLK Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, IHC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Tretter, Ross, Dordai, Desiderio: "Mimicry of pre-B cell receptor signaling by activation of the tyrosine kinase Blk." dans: The Journal of experimental medicine, Vol. 198, Issue 12, pp. 1863-73, (2003) (PubMed).

  • Antigène
    BLK (B Lymphoid Tyrosine Kinase (BLK))
    Autre désignation
    BLK (BLK Produits)
    Synonymes
    anticorps bltk, anticorps si:dkey-33i22.2, anticorps zgc:136231, anticorps MODY11, anticorps BLK proto-oncogene, Src family tyrosine kinase, anticorps B lymphoid kinase, anticorps blk, anticorps BLK, anticorps Blk
    Sujet

    Description: BLK ( B lymphoid tyrosine kinase), with 505-amino acid protein (about 56KDa), belongs to the Src non-receptor tyrosine kinases family.Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization, and membrane trafficking.Blk is expressed exclusively by B lymphocytes and it is thought to function in a signal transductory pathway specific to this lineage. B lymphoid expression of an active Blk mutant caused proliferation of B progenitor cells and enhanced responsiveness of these cells to interleukin 7. Thus, sustained activation of Blk induces responses normally associated with the pre-BCR.

    Aliases: MGC10442

    ID gène
    640
    HGNC
    640
    Pathways
    Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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