Calnexin anticorps

N° du produit ABIN969000

Cet anticorps anti-Calnexin est un anticorps Souris Monoclonal détectant Calnexin dans WB, ELISA et ICC. Adapté pour Humain. Ce Primary Antibody a été cité dans 3+ publications.

Aperçu rapide pour Calnexin anticorps (ABIN969000)

Antigène: Calnexin (CANX)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Calnexin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Clone: 3H4A7

Détail du produit anti-Calnexin anticorps

Fonction: Calnexin Antibody

Séquence: CEAAEERPWL WVVYILTVAL

Purification: Ascitic fluid

Immunogène: Synthetic peptide corresponding to aa (CEAAEERPWLWVVYILTVAL) of human Calnexin, conjugated to KLH.

Isotype: IgG2b

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Calnexin (ABIN969000)

Orlando: "The low-density lipoprotein receptor-related protein associates with calnexin, calreticulin, and protein disulfide isomerase in receptor-associated-protein-deficient fibroblasts." dans: Experimental cell research, Vol. 294, Issue 1, pp. 244-53, (2004) (PubMed).

Egan, Pearson, Weiner, Rajendran, Rubin, Glöckner-Pagel, Canny, Du, Lukacs, Caplan: "Curcumin, a major constituent of turmeric, corrects cystic fibrosis defects." dans: Science (New York, N.Y.), Vol. 304, Issue 5670, pp. 600-2, (2004) (PubMed).

Oda, Hosokawa, Wada, Nagata: "EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin." dans: Science (New York, N.Y.), Vol. 299, Issue 5611, pp. 1394-7, (2003) (PubMed).

Détails sur Calnexin

Antigène: Calnexin (CANX)

Autre désignation: Calnexin

Sujet: This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described.

Poids moléculaire: 90 kDa

ID gène: 821

UniProt: P27824

Pathways: Signalisation MAPK, Thyroid Hormone Synthesis