Cyclin B1 anticorps

N° du produit ABIN969005

L’anticorps Souris Monoclonal anti-Cyclin B1 a été validé pour WB, IHC et ELISA. Il convient pour détecter Cyclin B1 dans des échantillons de Humain. Il y a 2+ publications disponibles.

Aperçu rapide pour Cyclin B1 anticorps (ABIN969005)

Antigène: Cyclin B1 (CCNB1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cyclin B1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 1B10

Détail du produit anti-Cyclin B1 anticorps

Fonction: CCNB1 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human CCNB1 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Cyclin B1 (ABIN969005)

Zhang, Li, Guo, Cao, Zhao, Jiang, Ma, Yi, Li, Jiang, Wu, Wang, Si: "DH166, a beta-carboline derivative, inhibits the kinase activity of PLK1." dans: Cancer biology & therapy, Vol. 8, Issue 24, pp. 2374-83, (2010) (PubMed).

Okayama, Kumamoto, Saitou, Hayase, Kofunato, Sato, Miyamoto, Nakamura, Ohki, Sekikawa, Takenoshita: "CD44v6, MMP-7 and nuclear Cdx2 are significant biomarkers for prediction of lymph node metastasis in primary gastric cancer." dans: Oncology reports, Vol. 22, Issue 4, pp. 745-55, (2009) (PubMed).

Détails sur Cyclin B1

Antigène: Cyclin B1 (CCNB1)

Autre désignation: CCNB1

Sujet: The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. (provided by RefSeq) It has higher expression in tumor tissues .

Poids moléculaire: 60 kDa

ID gène: 891

UniProt: P14635

Pathways: Cycle Cellulaire, AMPK Signaling, Mitotic G1-G1/S Phases, M Phase