Cyclin B1 anticorps

N° du produit ABIN969006

Cet anticorps anti-Cyclin B1 est un anticorps Souris Monoclonal détectant Cyclin B1 dans WB, ELISA, FACS et ICC. Adapté pour Humain et Rat. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour Cyclin B1 anticorps (ABIN969006)

Antigène: Cyclin B1 (CCNB1)

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cyclin B1 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 5G6

Détail du produit anti-Cyclin B1 anticorps

Fonction: CCNB1 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human CCNB1 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Cyclin B1 (ABIN969006)

Chou, Yen, Lee, Chen: "Pro-apoptotic role of Cdc25A: activation of cyclin B1/Cdc2 by the Cdc25A C-terminal domain." dans: The Journal of biological chemistry, Vol. 285, Issue 23, pp. 17833-45, (2010) (PubMed).

Gustafsson, Zhao, Gustafsson, Dahlman-Wright: "RBCK1 drives breast cancer cell proliferation by promoting transcription of estrogen receptor alpha and cyclin B1." dans: Cancer research, Vol. 70, Issue 3, pp. 1265-74, (2010) (PubMed).

Détails sur Cyclin B1

Antigène: Cyclin B1 (CCNB1)

Autre désignation: CCNB1

Sujet: The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. (provided by RefSeq) It has higher expression in tumor tissues .

Poids moléculaire: 60 kDa

ID gène: 891

UniProt: P14635

Pathways: Cycle Cellulaire, AMPK Signaling, Mitotic G1-G1/S Phases, M Phase