CD94 anticorps

N° du produit ABIN969031

Cet anticorps Souris Monoclonal détecte spécifiquement CD94 dans FACS et ELISA. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour CD94 anticorps (ABIN969031)

Antigène: CD94 (KLRD1) (Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD94 est non-conjugé

Application: Flow Cytometry (FACS), ELISA

Clone: 1H1

Détail du produit anti-CD94 anticorps

Fonction: CD94 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human CD94 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-CD94 (ABIN969031)

Lonigro, Mirabile, Munda, Barchitta, Bottino, Fazzio, Di Cataldo, Agodi, Schilirò: "Association between high expression of natural killer related-genes (NCAM/CD94) and early death during induction in children with acute myeloid leukemia." dans: Leukemia, Vol. 22, Issue 9, pp. 1778-81, (2008) (PubMed).

Masilamani, Narayanan, Prieto, Borrego, Coligan: "Uncommon endocytic and trafficking pathway of the natural killer cell CD94/NKG2A inhibitory receptor." dans: Traffic (Copenhagen, Denmark), Vol. 9, Issue 6, pp. 1019-34, (2008) (PubMed).

Détails sur CD94

Antigène: CD94 (KLRD1) (Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1))

Autre désignation: CD94

Sujet: Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Tissue specificity: Natural killer cells.

Poids moléculaire: 21 kDa

ID gène: 3824

UniProt: Q13241