CEBPB anticorps

N° du produit ABIN969049

Cet anticorps Souris Monoclonal détecte spécifiquement CEBPB dans ELISA et FACS. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour CEBPB anticorps (ABIN969049)

Antigène: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CEBPB est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Clone: 3H9

Détail du produit anti-CEBPB anticorps

Fonction: CEBPB Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human CEBPB expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-CEBPB (ABIN969049)

Cappello, Zwergal, Kanclerski, Haas, Kandemir, Huber, Page, Brand: "C/EBPbeta enhances NF-kappaB-associated signalling by reducing the level of IkappaB-alpha." dans: Cellular signalling, Vol. 21, Issue 12, pp. 1918-24, (2009) (PubMed).

Détails sur CEBPB

Antigène: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Autre désignation: CEBPB

Sujet: The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. Tissue specificity: Expressed at low levels in the lung, kidney and spleen.

Poids moléculaire: 36 kDa

UniProt: P17676

Pathways: Interferon-gamma Pathway, Autophagy, Brown Fat Cell Differentiation