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CrkL anticorps

CRKL Reactivité: Humain WB, ELISA, FACS Hôte: Souris Monoclonal 5-00E-12 unconjugated
N° du produit ABIN969064
  • Antigène Voir toutes CrkL (CRKL) Anticorps
    CrkL (CRKL) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
    Reactivité
    • 99
    • 74
    • 29
    • 5
    • 1
    • 1
    Humain
    Hôte
    • 116
    • 10
    • 2
    • 1
    Souris
    Clonalité
    • 114
    • 14
    Monoclonal
    Conjugué
    • 44
    • 11
    • 10
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp CrkL est non-conjugé
    Application
    • 76
    • 44
    • 26
    • 26
    • 17
    • 15
    • 12
    • 12
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human CRKL expressed in E. coli.
    Clone
    5-00E-12
    Isotype
    IgG1
    Top Product
    Discover our top product CRKL Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Seo, Suenaga, Hatakeyama, Taiji, Imamoto: "Structural and functional basis of a role for CRKL in a fibroblast growth factor 8-induced feed-forward loop." dans: Molecular and cellular biology, Vol. 29, Issue 11, pp. 3076-87, (2009) (PubMed).

  • Antigène
    CrkL (CRKL) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
    Autre désignation
    CRKL (CRKL Produits)
    Synonymes
    anticorps CRKL, anticorps wu:fa55g05, anticorps wu:fj60e01, anticorps zgc:63469, anticorps 1110025F07Rik, anticorps AA589403, anticorps AI325100, anticorps Crkol, anticorps CRK like proto-oncogene, adaptor protein, anticorps v-crk avian sarcoma virus CT10 oncogene homolog-like, anticorps CRKL, anticorps crkl, anticorps Crkl
    Sujet

    Description: This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.

    Aliases: CRKL

    Poids moléculaire
    39 kDa
    ID gène
    1399
    HGNC
    1399
    Pathways
    Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor
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