FABP4 anticorps

N° du produit ABIN969126

Cet anticorps anti-FABP4 est un anticorps Souris Monoclonal détectant FABP4 dans ELISA. Adapté pour Humain. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour FABP4 anticorps (ABIN969126)

Antigène: FABP4 (Fatty Acid Binding Protein 4, Adipocyte (FABP4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FABP4 est non-conjugé

Application: ELISA

Clone: 9B8D

Détail du produit anti-FABP4 anticorps

Fonction: FABP4 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of FABP4 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-FABP4 (ABIN969126)

Tuncman, Erbay, Hom, De Vivo, Campos, Rimm, Hotamisligil: "A genetic variant at the fatty acid-binding protein aP2 locus reduces the risk for hypertriglyceridemia, type 2 diabetes, and cardiovascular disease." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 18, pp. 6970-5, (2006) (PubMed).

Gericke, Smith, Moore, Mendelsohn, Storch: "Adipocyte fatty acid-binding protein: interaction with phospholipid membranes and thermal stability studied by FTIR spectroscopy." dans: Biochemistry, Vol. 36, Issue 27, pp. 8311-7, (1997) (PubMed).

Détails sur FABP4

Antigène: FABP4 (Fatty Acid Binding Protein 4, Adipocyte (FABP4))

Autre désignation: FABP4

Sujet: Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long chain fatty acids, their coenzymes and other hydrophobic ligands and small molecules in the cytoplasm. It is thought that the role of these proteins includes fatty acid uptake, intracellular lipid transport and metabolism. FABP4 encodes the fatty acid binding protein found in adipocytes. FABP4 knockout mice fed a high-fat and high-calorie diet become obese but develop neither insulin resistance nor diabetes, suggesting that this protein might be a link between obesity and insulin resistance and diabetes A related study in humans indicated a similar pattern, suggesting that FABP4 may be a potential therapeutic target in the treatment of these disorders.

Poids moléculaire: 14 kDa

ID gène: 2167

UniProt: P15090

Pathways: Brown Fat Cell Differentiation