Fibulin 5 anticorps (AA 242-448)

N° du produit ABIN969131

L’anticorps Souris Monoclonal anti-Fibulin 5 a été validé pour IHC et ELISA. Il convient pour détecter Fibulin 5 dans des échantillons de Humain. Il y a 3+ publications disponibles.

Aperçu rapide pour Fibulin 5 anticorps (AA 242-448) (ABIN969131)

Antigène: Fibulin 5 (FBLN5)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Fibulin 5 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Clone: 1G6A4

Détail du produit anti-Fibulin 5 anticorps

Épitope: AA 242-448

Fonction: FBLN5 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of FBLN5 (aa242-448) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Fibulin 5 (ABIN969131)

Wang, LeMaire, Chen, Carter, Shen, Gan, Bartsch, Wilks, Utama, Ou, Thompson, Coselli, Wang: "Decreased expression of fibulin-5 correlates with reduced elastin in thoracic aortic dissection." dans: Surgery, Vol. 138, Issue 2, pp. 352-9, (2005) (PubMed).

Stone, Braun, Russell, Kuehn, Lotery, Moore, Eastman, Casavant, Sheffield: "Missense variations in the fibulin 5 gene and age-related macular degeneration." dans: The New England journal of medicine, Vol. 351, Issue 4, pp. 346-53, (2004) (PubMed).

Markova, Zou, Ringpfeil, Sasaki, Kostka, Timpl, Uitto, Chu: "Genetic heterogeneity of cutis laxa: a heterozygous tandem duplication within the fibulin-5 (FBLN5) gene." dans: American journal of human genetics, Vol. 72, Issue 4, pp. 998-1004, (2003) (PubMed).

Détails sur Fibulin 5

Antigène: Fibulin 5 (FBLN5)

Autre désignation: FBLN5

Sujet: FBLN5: fibulin 5. The protein is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling.

UniProt: Q9UBX5

Pathways: SARS-CoV-2 Protein Interactome