Fibrinogen beta Chain anticorps (AA 30-300)

N° du produit ABIN969136

Cet anticorps Souris Monoclonal détecte spécifiquement Fibrinogen beta Chain dans WB et ELISA. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour Fibrinogen beta Chain anticorps (AA 30-300) (ABIN969136)

Antigène: Fibrinogen beta Chain (FGB)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Fibrinogen beta Chain est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 1F9

Détail du produit anti-Fibrinogen beta Chain anticorps

Épitope: AA 30-300

Fonction: FGB Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human FGB (aa30-300) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Fibrinogen beta Chain (ABIN969136)

Koch, Hoppmann, Biele, Mueller, Schömig, Kastrati: "Fibrinogen genes and myocardial infarction: a haplotype analysis." dans: Arteriosclerosis, thrombosis, and vascular biology, Vol. 28, Issue 4, pp. 758-63, (2008) (PubMed).

Vu, Bolton-Maggs, Parr, Morris, de Moerloose, Neerman-Arbez: "Congenital afibrinogenemia: identification and expression of a missense mutation in FGB impairing fibrinogen secretion." dans: Blood, Vol. 102, Issue 13, pp. 4413-5, (2003) (PubMed).

Détails sur Fibrinogen beta Chain

Antigène: Fibrinogen beta Chain (FGB)

Autre désignation: FGB

Sujet: Fibrinogen beta chain, also known as FGB, is a gene found in humans and most other vertebrates with a similar system of blood coagulation.It is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.

Poids moléculaire: 52 kDa

ID gène: 2244

UniProt: P02675