Glucose-6-Phosphate Dehydrogenase anticorps

N° du produit ABIN969161

L’anticorps Souris Monoclonal anti-Glucose-6-Phosphate Dehydrogenase a été validé pour WB, IHC, ELISA et FACS. Il convient pour détecter Glucose-6-Phosphate Dehydrogenase dans des échantillons de Humain. Il y a 2+ publications disponibles.

Aperçu rapide pour Glucose-6-Phosphate Dehydrogenase anticorps (ABIN969161)

Antigène: Glucose-6-Phosphate Dehydrogenase (G6PD)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Glucose-6-Phosphate Dehydrogenase est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Clone: 5E12

Détail du produit anti-Glucose-6-Phosphate Dehydrogenase anticorps

Fonction: G6PD Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human G6PD expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Glucose-6-Phosphate Dehydrogenase (ABIN969161)

Louicharoen, Patin, Paul, Nuchprayoon, Witoonpanich, Peerapittayamongkol, Casademont, Sura, Laird, Singhasivanon, Quintana-Murci, Sakuntabhai: "Positively selected G6PD-Mahidol mutation reduces Plasmodium vivax density in Southeast Asians." dans: Science (New York, N.Y.), Vol. 326, Issue 5959, pp. 1546-9, (2009) (PubMed).

Brajovich, Rucci, Acosta, Cotorruelo, García Borrás, Racca, Biondi, Racca: "Effects of aging on antioxidant response and phagocytosis in senescent erythrocytes." dans: Immunological investigations, Vol. 38, Issue 6, pp. 551-9, (2009) (PubMed).

Détails sur Glucose-6-Phosphate Dehydrogenase

Antigène: Glucose-6-Phosphate Dehydrogenase (G6PD)

Autre désignation: G6PD

Sujet: This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 59 kDa

ID gène: 2539

UniProt: P11413

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones