HCK anticorps

N° du produit ABIN969187

Cet anticorps Souris Monoclonal détecte spécifiquement HCK dans ELISA et IHC. Il présente une réactivité avec des échantillons de Humain. Il a été cité dans 2+ publications.

Aperçu rapide pour HCK anticorps (ABIN969187)

Antigène: HCK (Hemopoietic Cell Kinase (HCK))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HCK est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Clone: 3D12E10

Détail du produit anti-HCK anticorps

Fonction: HCK Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of HCK expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-HCK (ABIN969187)

Schnoor: "What I learned in Europe...." dans: Environmental science & technology, Vol. 41, Issue 3, pp. 667, (2007) (PubMed).

Selimoglu, Ertekin, Altinkaynak: "Hyper-CK-emia in pediatric celiac disease: prevalence and clinical importance." dans: Journal of clinical gastroenterology, Vol. 41, Issue 7, pp. 667-70, (2007) (PubMed).

Détails sur HCK

Antigène: HCK (Hemopoietic Cell Kinase (HCK))

Autre désignation: HCK

Sujet: Hemopoietic cell kinase.The protein encoded by this gene is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization.

UniProt: P08631

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling