JUP anticorps

N° du produit ABIN969225

Cet anticorps anti-JUP est un anticorps Souris Monoclonal détectant JUP dans WB, IHC, ELISA et ICC. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour JUP anticorps (ABIN969225)

Antigène: JUP (Junction Plakoglobin (JUP))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp JUP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Clone: 4C12

Détail du produit anti-JUP anticorps

Fonction: JUP Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human JUP expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-JUP (ABIN969225)

Shair, Schnegg, Raab-Traub: "Epstein-Barr virus latent membrane protein-1 effects on junctional plakoglobin and induction of a cadherin switch." dans: Cancer research, Vol. 69, Issue 14, pp. 5734-42, (2009) (PubMed).

Détails sur JUP

Antigène: JUP (Junction Plakoglobin (JUP))

Autre désignation: JUP

Sujet: This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene, however, not all transcripts have been fully described.

Poids moléculaire: 82 kDa

ID gène: 3728

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location