KARS anticorps (AA 90-174)

N° du produit ABIN969226

Cet anticorps Souris Monoclonal détecte spécifiquement KARS dans IHC et ELISA. Il présente une réactivité envers Humain et a été mentionné dans 4+ publications.

Aperçu rapide pour KARS anticorps (AA 90-174) (ABIN969226)

Antigène: KARS (Lysyl-tRNA Synthetase (KARS))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KARS est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Clone: 8G12C1

Détail du produit anti-KARS anticorps

Épitope: AA 90-174

Fonction: KARS Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of KARS(aa90-174) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-KARS (ABIN969226)

Sampath, Mazumder, Seshadri, Gerber, Chavatte, Kinter, Ting, Dignam, Kim, Driscoll, Fox: "Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translation." dans: Cell, Vol. 119, Issue 2, pp. 195-208, (2004) (PubMed).

Sang Lee, Gyu Park, Park, Seol, Lee, Kim: "Interaction network of human aminoacyl-tRNA synthetases and subunits of elongation factor 1 complex." dans: Biochemical and biophysical research communications, Vol. 291, Issue 1, pp. 158-64, (2002) (PubMed).

Cen, Khorchid, Javanbakht, Gabor, Stello, Shiba, Musier-Forsyth, Kleiman: "Incorporation of lysyl-tRNA synthetase into human immunodeficiency virus type 1." dans: Journal of virology, Vol. 75, Issue 11, pp. 5043-8, (2001) (PubMed).

Tolkunova, Park, Xia, King, Davidson: "The human lysyl-tRNA synthetase gene encodes both the cytoplasmic and mitochondrial enzymes by means of an unusual alternative splicing of the primary transcript." dans: The Journal of biological chemistry, Vol. 275, Issue 45, pp. 35063-9, (2000) (PubMed).

Détails sur KARS

Antigène: KARS (Lysyl-tRNA Synthetase (KARS))

Autre désignation: KARS

Sujet: KARS: lysyl-tRNA synthetase. Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.

ID gène: 3735

UniProt: Q15046