MERTK anticorps

N° du produit ABIN969283

Cet anticorps Souris Monoclonal détecte spécifiquement MERTK dans ELISA. Il présente une réactivité envers Humain et a été mentionné dans 3+ publications.

Aperçu rapide pour MERTK anticorps (ABIN969283)

Antigène: MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MERTK est non-conjugé

Application: ELISA

Clone: 7E5G1

Détail du produit anti-MERTK anticorps

Fonction: MER Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of MER expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-MERTK (ABIN969283)

McGough, Cummings: "Coeliac disease: a diverse clinical syndrome caused by intolerance of wheat, barley and rye." dans: The Proceedings of the Nutrition Society, Vol. 64, Issue 4, pp. 434-50, (2005) (PubMed).

Allouache, Gawande, Tubiana-Hulin, Tubiana-Mathieu, Piperno-Neumann, Mefti, Bozec, Genot: "First-line therapy with gemcitabine and paclitaxel in locally, recurrent or metastatic breast cancer: a phase II study." dans: BMC cancer, Vol. 5, pp. 151, (2005) (PubMed).

Seguineau, Soudant, Moal, Delaporte, Miner, Quéré, Samain: "Techniques for delivery of arachidonic acid to Pacific oyster, Crassostrea gigas, spat." dans: Lipids, Vol. 40, Issue 9, pp. 931-9, (2005) (PubMed).

Détails sur MERTK

Antigène: MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

Autre désignation: MER

Sujet: MER (c-mer proto-oncogene tyrosine kinase) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. MER has been identified as a tyrosine kinase potentially involved in the development of glioblastomas. It is expressed at highest levels in ovary, prostate, lung and kidney. Gas6, a growth arrest specific gene, and the related anticoagulation factor Protein S have been identified as ligands for the UFO family of receptors. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

UniProt: Q12866

Pathways: Signalisation RTK