MSI2 anticorps

N° du produit ABIN969295

Détail du produit anti-MSI2 anticorps

Antigène: MSI2 (Musashi Homolog 2 (MSI2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MSI2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: purified

Immunogène: Purified recombinant fragment of human MSI2 expressed in E. coli.

Clone: 2C11

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-MSI2 (ABIN969295)

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." dans: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

De Weer, Speleman, Cauwelier, Van Roy, Yigit, Verhasselt, De Moerloose, Benoit, Noens, Selleslag, Lippert, Struski, Bastard, De Paepe, Vandenberghe, Hagemeijer, Dastugue, Poppe: "EVI1 overexpression in t(3;17) positive myeloid malignancies results from juxtaposition of EVI1 to the MSI2 locus at 17q22." dans: Haematologica, Vol. 93, Issue 12, pp. 1903-7, (2008) (PubMed).

Détails sur MSI2

Antigène: MSI2 (Musashi Homolog 2 (MSI2))

Autre désignation: MSI2 (MSI2 Produits)

Synonymes: anticorps MSI2H, anticorps 1700105C15Rik, anticorps AI451722, anticorps AI563628, anticorps AW489193, anticorps Msi2h, anticorps RGD1560397, anticorps MSI2, anticorps musashi-2, anticorps musashi2, anticorps xrp1, anticorps msi2, anticorps zgc:174035, anticorps zgc:63812, anticorps cb746, anticorps fi47b09, anticorps wu:fb02d08, anticorps wu:fi32d12, anticorps wu:fi47b09, anticorps musashi RNA binding protein 2, anticorps musashi RNA-binding protein 2, anticorps musashi RNA binding protein 2 S homeolog, anticorps musashi RNA-binding protein 2b, anticorps musashi RNA-binding protein 2a, anticorps MSI2, anticorps Msi2, anticorps msi2.S, anticorps msi2, anticorps msi2b, anticorps msi2a

Sujet:

Description: Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously at low levels, Msi2 functions as an RNA binding protein that, by regulating the expression of target mRNAs, is thought to play a role in the proliferation and maintenance of stem cells within the central nervous system. Msi2 is subject to posttranslational phosphorylation and is upregulated in response to brain injury, suggesting a role in healing and brain tissue regeneration. Chromosomal aberrations involving the Msi2 gene are associated with the progression of chronic myeloid leukemia. Multiple isoforms of Msi2 exist due to alternative splicing events.Tissue specificity: Ubiquitous, detected at low levels.

Aliases: MSI2H, MGC3245, FLJ36569, MSI2

Poids moléculaire: 35 kDa

ID gène: 124540

HGNC: 124540