NCOR1 anticorps (AA 1-192)

N° du produit ABIN969310

Cet anticorps Souris Monoclonal détecte spécifiquement NCOR1 dans ELISA et IHC. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour NCOR1 anticorps (AA 1-192) (ABIN969310)

Antigène: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NCOR1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Clone: 7A7A9

Détail du produit anti-NCOR1 anticorps

Épitope: AA 1-192

Fonction: NCOR1 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of NCOR1 (aa1-192) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-NCOR1 (ABIN969310)

Atsumi, Tomita, Kiyoi, Naoe: "Histone deacetylase 3 (HDAC3) is recruited to target promoters by PML-RARalpha as a component of the N-CoR co-repressor complex to repress transcription in vivo." dans: Biochemical and biophysical research communications, Vol. 345, Issue 4, pp. 1471-80, (2006) (PubMed).

Zhang, Yoon, Wong: "JMJD2A is a novel N-CoR-interacting protein and is involved in repression of the human transcription factor achaete scute-like homologue 2 (ASCL2/Hash2)." dans: Molecular and cellular biology, Vol. 25, Issue 15, pp. 6404-14, (2005) (PubMed).

Détails sur NCOR1

Antigène: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Autre désignation: NCOR1

Sujet: NCOR1: Nuclear receptor co-repressor 1. This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.

ID gène: 9611

UniProt: O75376

Pathways: Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process