Prostate Specific Antigen anticorps (AA 26-251)
Aperçu rapide pour Prostate Specific Antigen anticorps (AA 26-251) (ABIN969369)
Antigène
Voir toutes Prostate Specific Antigen (PSA) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 26-251
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Fonction
- PSA (KLK3) Antibody
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Purification
- Ascitic fluid
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Immunogène
- Purified recombinant fragment of KLK3 (aa26-251) expressed in E. Coli.
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Isotype
- IgG1
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Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Measurement of serum prostate cancer markers using a nanopore thin film based optofluidic chip." dans: Biosensors & bioelectronics, Vol. 77, pp. 491-8, (2015) (PubMed).
: "Structural model of human PSA: a target for prostate cancer therapy." dans: Chemical biology & drug design, Vol. 70, Issue 3, pp. 261-7, (2007) (PubMed).
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: "Measurement of serum prostate cancer markers using a nanopore thin film based optofluidic chip." dans: Biosensors & bioelectronics, Vol. 77, pp. 491-8, (2015) (PubMed).
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- Prostate Specific Antigen (PSA)
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Autre désignation
- PSA (KLK3)
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Sujet
- Kallikrein-related peptidase 3.Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.
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ID gène
- 354
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UniProt
- P07288
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Pathways
- Système du Complément
Antigène
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