SMAD3 anticorps

N° du produit ABIN969402

Cité dans 2 publications. Cet anticorps anti-SMAD3 Monoclonal Souris (Clone 5G11) (ABIN969402) détecte spécifiquement SMAD3 dans WB, ELISA et ICC. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour SMAD3 anticorps (ABIN969402)

Antigène: SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SMAD3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Clone: 5G11

Détail du produit anti-SMAD3 anticorps

Fonction: SMAD3 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human SMAD3 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-SMAD3 (ABIN969402)

Luo, Phillips, Fraser: "Bone morphogenetic protein-7 inhibits proximal tubular epithelial cell Smad3 signaling via increased SnoN expression." dans: The American journal of pathology, Vol. 176, Issue 3, pp. 1139-47, (2010) (PubMed).

Tseng, Vittinghoff, Musone, Lin, Whiteman, Pawlikowska, Kwok, Olgin, Aouizerat: "Association of TGFBR2 polymorphism with risk of sudden cardiac arrest in patients with coronary artery disease." dans: Heart rhythm : the official journal of the Heart Rhythm Society, Vol. 6, Issue 12, pp. 1745-50, (2009) (PubMed).

Détails sur SMAD3

Antigène: SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

Autre désignation: SMAD3

Sujet: SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

Poids moléculaire: 48 kDa

UniProt: P84022

Pathways: Cycle Cellulaire, Chromatin Binding, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Autophagy