SOX2 anticorps (AA 1-170)

N° du produit ABIN969413

L’anticorps Souris Monoclonal anti-SOX2 a été validé pour ELISA. Il convient pour détecter SOX2 dans des échantillons de Humain. Il y a 2+ publications disponibles.

Aperçu rapide pour SOX2 anticorps (AA 1-170) (ABIN969413)

Antigène: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SOX2 est non-conjugé

Application: ELISA

Clone: 10F10C9

Détail du produit anti-SOX2 anticorps

Épitope: AA 1-170

Fonction: SOX2 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of SOX2 (aa1-170) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-SOX2 (ABIN969413)

Park, Zhao, West, Yabuuchi, Huo, Ince, Lerou, Lensch, Daley: "Reprogramming of human somatic cells to pluripotency with defined factors." dans: Nature, Vol. 451, Issue 7175, pp. 141-6, (2008) (PubMed).

Baer, Eriksson, Faull, Rees, Curtis: "Sox-2 is expressed by glial and progenitor cells and Pax-6 is expressed by neuroblasts in the human subventricular zone." dans: Experimental neurology, Vol. 204, Issue 2, pp. 828-31, (2007) (PubMed).

Détails sur SOX2

Antigène: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Autre désignation: SOX2

Sujet: SOX2: SRY (sex determining region Y)-box 2. Entrez Protein NP_003097. It is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).

Poids moléculaire: 34.3 kDa

ID gène: 6657

UniProt: P48431

Pathways: Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis