SRA1 anticorps

N° du produit ABIN969416

Il existe 3+ publications pour ce produit. L’anticorps anti-SRA1 Monoclonal Souris est utilisé pour la détection de SRA1 dans des échantillons de Humain. Il a été validé pour ELISA et IHC.

Aperçu rapide pour SRA1 anticorps (ABIN969416)

Antigène: SRA1 (Steroid Receptor RNA Activator 1 (SRA1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SRA1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Clone: 1D4H8

Détail du produit anti-SRA1 anticorps

Fonction: SRA Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of SRA expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-SRA1 (ABIN969416)

Chooniedass-Kothari, Hamedani, Troup, Hubé, Leygue: "The steroid receptor RNA activator protein is expressed in breast tumor tissues." dans: International journal of cancer. Journal international du cancer, Vol. 118, Issue 4, pp. 1054-9, (2006) (PubMed).

Chooniedass-Kothari, Emberley, Hamedani, Troup, Wang, Czosnek, Hube, Mutawe, Watson, Leygue: "The steroid receptor RNA activator is the first functional RNA encoding a protein." dans: FEBS letters, Vol. 566, Issue 1-3, pp. 43-7, (2004) (PubMed).

Lanz, Chua, Barron, Söder, DeMayo, OMalley: "Steroid receptor RNA activator stimulates proliferation as well as apoptosis in vivo." dans: Molecular and cellular biology, Vol. 23, Issue 20, pp. 7163-76, (2003) (PubMed).

Détails sur SRA1

Antigène: SRA1 (Steroid Receptor RNA Activator 1 (SRA1))

Autre désignation: SRA

Sujet: Steroid receptor RNA activator 1 (SRA), with 237-amino acid protein (about 27 kDa), belongs to the growing family of functional non-coding RNAs. SRA was originally described as the first functional noncoding RNA able to specifically coactivate the activity of steroid receptors. Specifically, SRA exists as both an RNA transcript that forms a complex with steroid receptor coactivator-1 and as a stably expressed protein. Its expression is strongly up-regulated in many human tumors of the breast, uterus, and ovary, suggesting a potential role in pathogenesis. Although coactivation of steroid-dependent transcription by SRA is accompanied by a proliferative response, overexpression is not in itself sufficient to induce turmorigenesis.

UniProt: Q9HD15

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development