Synaptophysin anticorps

N° du produit ABIN969428

L’anticorps Souris Monoclonal anti-Synaptophysin a été validé pour WB, IHC et ELISA. Il convient pour détecter Synaptophysin dans des échantillons de Humain et Rat. Il y a 3+ publications disponibles.

Aperçu rapide pour Synaptophysin anticorps (ABIN969428)

Antigène: Synaptophysin (SYP)

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Synaptophysin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 7H12

Détail du produit anti-Synaptophysin anticorps

Fonction: SYP Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of SYP expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Synaptophysin (ABIN969428)

Gulubova, Vlaykova: "Chromogranin A-, serotonin-, synaptophysin- and vascular endothelial growth factor-positive endocrine cells and the prognosis of colorectal cancer: an immunohistochemical and ultrastructural study." dans: Journal of gastroenterology and hepatology, Vol. 23, Issue 10, pp. 1574-85, (2009) (PubMed).

Sterlacci, Fiegl, Hilbe, Auberger, Mikuz, Tzankov: "Clinical relevance of neuroendocrine differentiation in non-small cell lung cancer assessed by immunohistochemistry: a retrospective study on 405 surgically resected cases." dans: Virchows Archiv : an international journal of pathology, Vol. 455, Issue 2, pp. 125-32, (2009) (PubMed).

Xu, Dai, Xiang, Zhao, Ruan, Cheng, Zheng, Shu: "Nutritional factors in relation to endometrial cancer: a report from a population-based case-control study in Shanghai, China." dans: International journal of cancer. Journal international du cancer, Vol. 120, Issue 8, pp. 1776-81, (2007) (PubMed).

Détails sur Synaptophysin

Antigène: Synaptophysin (SYP)

Autre désignation: SYP

Sujet: Synaptophysin (p38) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells.Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore. Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases. Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex.

Poids moléculaire: 33.8 kDa

ID gène: 6855

UniProt: P08247

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity