EPH Receptor B6 anticorps

N° du produit ABIN969479

L’anticorps Souris Monoclonal anti-EPH Receptor B6 a été validé pour WB, ELISA et IHC. Il convient pour détecter EPH Receptor B6 dans des échantillons de Humain. Il y a 2+ publications disponibles.

Aperçu rapide pour EPH Receptor B6 anticorps (ABIN969479)

Antigène: EPH Receptor B6 (EPHB6)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EPH Receptor B6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 8E7H12

Détail du produit anti-EPH Receptor B6 anticorps

Fonction: EphB6 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of EphB6 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-EPH Receptor B6 (ABIN969479)

Ogawa, Wada, Okada, Harada, Nakajima, Pasquale, Tsuyama: "EphB2 and ephrin-B1 expressed in the adult kidney regulate the cytoarchitecture of medullary tubule cells through Rho family GTPases." dans: Journal of cell science, Vol. 119, Issue Pt 3, pp. 559-70, (2006) (PubMed).

Matsuoka, Obama, Kelly, Matsui, Nakamoto: "Biphasic functions of the kinase-defective Ephb6 receptor in cell adhesion and migration." dans: The Journal of biological chemistry, Vol. 280, Issue 32, pp. 29355-63, (2005) (PubMed).

Détails sur EPH Receptor B6

Antigène: EPH Receptor B6 (EPHB6)

Autre désignation: EphB6

Sujet: EPH receptor B6 (EphB6), with 1006-amino acid protein(~ 110 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. Eph receptors and ephrin ligands are membrane-bound cell-cell communication molecules with well-defined functions in development. EphB6 is expressed both in a variety of embryonic and adult tissues. EphB6 is a unique member in the Eph family of receptor tyrosine kinases in that its kinase domain contains several alterations in conserved amino acids and is catalytically inactive. EphB6 can both positively and negatively regulate cell adhesion and migration and tyrosine phosphorylation of the receptor by an Src family kinase acts as the molecular switch for the functional transition.

UniProt: O15197

Pathways: Signalisation RTK, Hormone Transport