SNCG anticorps

N° du produit ABIN969490

Cet anticorps Souris Monoclonal détecte spécifiquement SNCG dans IHC et ELISA. Il présente une réactivité avec des échantillons de Humain. Il a été cité dans 2+ publications.

Aperçu rapide pour SNCG anticorps (ABIN969490)

Antigène: SNCG (Synuclein, gamma (Breast Cancer-Specific Protein 1) (SNCG))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SNCG est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Clone: 1H10D2

Détail du produit anti-SNCG anticorps

Fonction: SNCG (breast cancer-specific protein 1) Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of SNCG expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-SNCG (ABIN969490)

Surgucheva, McMahon, Surguchov: "gamma-synuclein has a dynamic intracellular localization." dans: Cell motility and the cytoskeleton, Vol. 63, Issue 8, pp. 447-58, (2006) (PubMed).

Brown, Lasek: "Polylysine cross-links axoplasmic neurofilaments into tight bundles." dans: Cell motility and the cytoskeleton, Vol. 31, Issue 1, pp. 9-21, (1995) (PubMed).

Détails sur SNCG

Antigène: SNCG (Synuclein, gamma (Breast Cancer-Specific Protein 1) (SNCG))

Autre désignation: SNCG (breast cancer-specific protein 1)

Sujet: SNCG(also designated gamma-synuclein or breast cancer-specific protein 1),with 127-amino acid protein(about 14 kDa), belongs to the synuclein family, which also includes alpha- and beta- synuclein.Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals,while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.

ID gène: 6623

UniProt: O76070