Cytokeratin 5 anticorps

N° du produit ABIN969508

Cet anticorps Souris Monoclonal détecte spécifiquement Cytokeratin 5 dans WB, IHC, ELISA, FACS et ICC. Il présente une réactivité envers Humain, Souris et Singe et a été mentionné dans 2+ publications.

Aperçu rapide pour Cytokeratin 5 anticorps (ABIN969508)

Antigène: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Reactivité: Humain, Souris, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cytokeratin 5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 2C2

Détail du produit anti-Cytokeratin 5 anticorps

Fonction: CK5 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CK5 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Cytokeratin 5 (ABIN969508)

Grin, OMalley, Mulligan: "Cytokeratin 5 and estrogen receptor immunohistochemistry as a useful adjunct in identifying atypical papillary lesions on breast needle core biopsy." dans: The American journal of surgical pathology, Vol. 33, Issue 11, pp. 1615-23, (2009) (PubMed).

Sugiyama-Fukamatsu, Suzuki, Nakanishi, Iwatsuki: "Epidermolysis bullosa nevus arising in a patient with Dowling-Meara type epidermolysis bullosa simplex with a novel K5 mutation." dans: The Journal of dermatology, Vol. 36, Issue 8, pp. 447-52, (2009) (PubMed).

Détails sur Cytokeratin 5

Antigène: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Autre désignation: CK5

Sujet: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Poids moléculaire: 62.3 kDa

ID gène: 3852

UniProt: P13647