GRIA2 anticorps (AA 652-807)

N° du produit ABIN969524

L’anticorps Souris Monoclonal anti-GRIA2 a été validé pour WB, ELISA et FACS. Il convient pour détecter GRIA2 dans des échantillons de Humain. Il y a 2+ publications disponibles.

Aperçu rapide pour GRIA2 anticorps (AA 652-807) (ABIN969524)

Antigène: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GRIA2 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Clone: 7G6

Détail du produit anti-GRIA2 anticorps

Épitope: AA 652-807

Fonction: GRIA2 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human GRIA2 (AA: 652-807) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-GRIA2 (ABIN969524)

Yu, Wu, Fu, Cheng, Yang, Chen, Long, Chen, Wang: "Aging-related alterations in the expression and distribution of GluR2 and PICK1 in the rat hippocampus." dans: Neuroscience letters, Vol. 497, Issue 1, pp. 42-5, (2011) (PubMed).

Shen, Jin: "[GluR2 expression in the developing rat inferior colliculus and the relationship with development of synapse]." dans: Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, Vol. 24, Issue 4, pp. 173-6, (2010) (PubMed).

Détails sur GRIA2

Antigène: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Autre désignation: GRIA2

Sujet: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing (Q/R and R/G), which is thought to render the channels impermeable to Ca(2+), and to affect the kinetic aspects of these channels in rat brain. Alternative splicing, resulting in transcript variants encoding different isoforms (flip and flop), has been noted for this gene.

Poids moléculaire: 98.8 kDa

ID gène: 2891

UniProt: P42262

Pathways: Signalisation PI3K-Akt