MELK anticorps (AA 637-651)

N° du produit ABIN969538

Cet anticorps Souris Monoclonal détecte spécifiquement MELK dans ELISA, IHC, ICC et FACS. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour MELK anticorps (AA 637-651) (ABIN969538)

Antigène: MELK (Maternal Embryonic Leucine Zipper Kinase (MELK))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MELK est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 2G2

Détail du produit anti-MELK anticorps

Épitope: AA 637-651

Fonction: MELK Antibody

Séquence: VYKRLVEDIL SSCKV

Purification: Purified antibody

Immunogène: Synthesized peptide of human MELK(AA: 637-651:C-VYKRLVEDILSSCKV).

Isotype: IgG2a

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-MELK (ABIN969538)

Nakano, Joshi, Visnyei, Hu, Watanabe, Lam, Wexler, Saigusa, Nakamura, Laks, Mischel, Viapiano, Kornblum: "Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway." dans: Neuro-oncology, Vol. 13, Issue 6, pp. 622-34, (2011) (PubMed).

Pickard, Green, Ellis, Caldas, Hedge, Mourtada-Maarabouni, Williams: "Dysregulated expression of Fau and MELK is associated with poor prognosis in breast cancer." dans: Breast cancer research : BCR, Vol. 11, Issue 4, pp. R60, (2009) (PubMed).

Détails sur MELK

Antigène: MELK (Maternal Embryonic Leucine Zipper Kinase (MELK))

Autre désignation: MELK

Sujet: Maternal embryonic leucine-zipper kinase (MELK) is a key regulator of survival of stemlike GBM cells in vitro. MELK expression is increased in breast cancer tissue and this increase is also associated with poor patient survival, as predicted for a candidate oncogene.

Poids moléculaire: 74.6 kDa

ID gène: 9833

UniProt: Q14680