NEDD8 anticorps (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8)

Details for Product anti-NEDD8 Antibody No. ABIN969547, Fournisseur: Connectez-vous pour afficher
Antigène
  • NEDD-8
  • Rub1
  • CG10679
  • Dmel\\CG10679
  • NEDD8
  • dNEDD8
  • nedd8
  • ubiquitin
  • si:zc14a17.5
  • GB17785
  • DDBDRAFT_0218116
  • DDBDRAFT_0238041
  • DDB_0218116
  • DDB_0238041
  • nedd8.S
  • neural precursor cell expressed, developmentally down-regulated 8
  • neural precursor cell expressed, developmentally down-regulated gene 8
  • CG10679 gene product from transcript CG10679-RB
  • Nedd8
  • ubiquitin-like protein Nedd8
  • neural precursor cell expressed, developmentally down-regulated 8 L homeolog
  • NEDD8
  • Nedd8
  • nedd8
  • nedd8.L
Reactivité
Humain
124
66
60
6
4
4
3
3
1
Hôte
Souris
100
26
5
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp NEDD8 est non-conjugé
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
117
70
60
29
24
21
13
13
10
5
4
4
2
2
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène Purified recombinant fragment of human NEDD8 expressed in E. Coli.
Clone 5B8
Isotype IgG1
Purification Purified
Plasmids, Primers & others Plasmids, Primers & others NEDD8 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation NEDD8 (NEDD8 Antibody Extrait)
Sujet Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.Tissue specificity: Highly expressed in heart, skeletal muscle, spleen, thymus, prostate, testis, ovary, colon and leukocytes.
Poids moléculaire 9 kDa
ID gène 4738
HGNC 4738
Indications d'application ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C,-20 °C
Stockage commentaire 4°C, -20°C for long term storage
Images (Fournisseur)
ELISA image for anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) antibody (ABIN969547) Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 n...
Flow Cytometry (FACS) image for anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) antibody (ABIN969547) Figure 2: Flow cytometric analysis of Hela cells using NEDD8 mouse mAb (green) and ne...
Immunocytochemistry (ICC) image for anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) antibody (ABIN969547) Figure 3: Immunofluorescence analysis of Hela cells using NEDD8 mouse mAb (green) . R...
Immunohistochemistry (IHC) image for anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) antibody (ABIN969547) Figure 4: Immunohistochemical analysis of paraffin-embedded prostate cancer tissues u...
Western Blotting (WB) image for anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) antibody (ABIN969547) Figure 5: Western blot analysis using NEDD8 mouse mAb against C6 (1) and Hela (2) cel...
Western Blotting (WB) image for anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) antibody (ABIN969547) Figure 6: Western blot analysis using NEDD8 mAb against human NEDD8 (AA: 1-81) recomb...
Produit citée dans: Ohki, Funatsu, Konishi, Chiba: "The mechanism of poly-NEDD8 chain formation in vitro." dans: Biochemical and biophysical research communications, Vol. 381, Issue 3, pp. 443-7, 2009 (PubMed).

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