NOS2 anticorps

N° du produit ABIN969551

2+ publications sont disponibles pour ce produit. L’anticorps anti-NOS2 Monoclonal produit chez le Souris a été validé pour WB, IHC, ELISA et FACS. Il convient pour la détection de NOS2 dans des échantillons provenant de Humain et Souris. }

Aperçu rapide pour NOS2 anticorps (ABIN969551)

Antigène: NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NOS2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Clone: 4E5

Détail du produit anti-NOS2 anticorps

Fonction: NOS2 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human NOS2 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-NOS2 (ABIN969551)

Huang, Ratovitski: "Phosphorylated TP63 induces transcription of RPN13, leading to NOS2 protein degradation." dans: The Journal of biological chemistry, Vol. 285, Issue 53, pp. 41422-31, (2010) (PubMed).

Granath, Norrby-Teglund, Uddman, Cardell: "Reduced iNOS expression in adenoids from children with otitis media with effusion." dans: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, Vol. 21, Issue 8, pp. 1151-6, (2010) (PubMed).

Détails sur NOS2

Antigène: NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))

Autre désignation: NOS2

Sujet: Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17.

Poids moléculaire: 131 kDa

ID gène: 4843

UniProt: P35228

Pathways: Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Inositol Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process