PAI1 anticorps

N° du produit ABIN969566

L’anticorps Souris Monoclonal anti-PAI1 a été validé pour IHC, ELISA et FACS. Il convient pour détecter PAI1 dans des échantillons de Humain. Il y a 2+ publications disponibles.

Aperçu rapide pour PAI1 anticorps (ABIN969566)

Antigène: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PAI1 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Clone: 1D5

Détail du produit anti-PAI1 anticorps

Fonction: SERPINE1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human SERPINE1 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-PAI1 (ABIN969566)

Oh, Olman, Benveniste: "CXCL12-mediated induction of plasminogen activator inhibitor-1 expression in human CXCR4 positive astroglioma cells." dans: Biological & pharmaceutical bulletin, Vol. 32, Issue 4, pp. 573-7, (2009) (PubMed).

Zee, Bubes, Shrivastava, Ridker, Glynn: "Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach." dans: Clinica chimica acta; international journal of clinical chemistry, Vol. 402, Issue 1-2, pp. 189-92, (2009) (PubMed).

Détails sur PAI1

Antigène: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Autre désignation: SERPINE1

Sujet: This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 45 kDa

UniProt: P05121

Pathways: Signalisation p53, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration