Thrombopoietin anticorps

N° du produit ABIN969571

Cet anticorps Souris Monoclonal détecte spécifiquement Thrombopoietin dans ELISA et FACS. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour Thrombopoietin anticorps (ABIN969571)

Antigène: Thrombopoietin (THPO)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Thrombopoietin est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Clone: 1B11

Détail du produit anti-Thrombopoietin anticorps

Fonction: THPO Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human THPO expressed in E. Coli.

Isotype: IgG2a

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Thrombopoietin (ABIN969571)

Graziano, Carone, Panza, Marino, Magini, Romeo, Pession, Seri: "Association of hereditary thrombocythemia and distal limb defects with a thrombopoietin gene mutation." dans: Blood, Vol. 114, Issue 8, pp. 1655-7, (2009) (PubMed).

Eissa, Gad, Rabie, El-Gayar: "Thrombopoietin level in patients with chronic liver diseases." dans: Annals of hepatology, Vol. 7, Issue 3, pp. 235-44, (2008) (PubMed).

Détails sur Thrombopoietin

Antigène: Thrombopoietin (THPO)

Autre désignation: THPO

Sujet: Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Alternate splicing results in multiple transcript variants of this gene.

Poids moléculaire: 37.8 kDa

UniProt: P40225

Pathways: Signalistation JAK/STAT, Hormone Activity