YAP1 anticorps

N° du produit ABIN969574

Cet anticorps Souris Monoclonal détecte spécifiquement YAP1 dans WB, ELISA, IHC et FACS. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour YAP1 anticorps (ABIN969574)

Antigène: YAP1 (Yes-Associated Protein 1 (YAP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp YAP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 1A12

Détail du produit anti-YAP1 anticorps

Fonction: YAP1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human YAP1 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-YAP1 (ABIN969574)

Fernandez-L, Northcott, Dalton, Fraga, Ellison, Angers, Taylor, Kenney: "YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation." dans: Genes & development, Vol. 23, Issue 23, pp. 2729-41, (2009) (PubMed).

Zhang, Ji, Yu, Overholtzer, Smolen, Wang, Brugge, Dyson, Haber: "YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway." dans: Nature cell biology, Vol. 11, Issue 12, pp. 1444-50, (2009) (PubMed).

Détails sur YAP1

Antigène: YAP1 (Yes-Associated Protein 1 (YAP1))

Autre désignation: YAP1

Sujet: This gene encodes the human ortholog of chicken YAP protein which binds to the SH3 domain of the Yes proto-oncogene product. This protein contains a WW domain that is found in various structural, regulatory and signaling molecules in yeast, nematode, and mammals, and may be involved in protein-protein interaction.

UniProt: P46937

Pathways: Signalisation MAPK, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha