APAF1 Produits
(Apoptotic Peptidase Activating Factor 1 (APAF1))
Catégories
This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.
Catégories APAF1 en vedette
APAF1 Anticorps
High quality antibodies with extensive validation data.
APAF1 Kits ELISA
Reliable ELISA kits for a wide range of species.
APAF1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
APAF1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (7)
N° du produit
ABIN1678685
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
- (5)
N° du produit
ABIN7433081
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, ICC, FACS, Neut
Validations
- (5)
N° du produit
ABIN5611196
Quantité
0.1 mg
Fiche technique
Fiche technique
APAF1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6964972
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6964971
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6953881
Quantité
96 tests
Fiche technique
Fiche technique
APAF1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1345275
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3089138
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3132252
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits APAF1
: "Optimization of Experimental Variables Influencing Apoptosome Biosensor in HEK293T Cells." dans: Sensors (Basel, Switzerland), Vol. 20, Issue 6, (2020) (PubMed).: "A new split-luciferase complementation assay identifies pentachlorophenol as an inhibitor of apoptosome formation." dans: FEBS open bio, Vol. 9, Issue 7, pp. 1194-1203, (2020) (PubMed).
: "Apoptosome formation upon overexpression of native and truncated Apaf-1 in cell-free and cell-based systems." dans: Archives of biochemistry and biophysics, Vol. 642, pp. 46-51, (2019) (PubMed).
: "LY333531, a PKCβ inhibitor, attenuates glomerular endothelial cell apoptosis in the early stage of mouse diabetic nephropathy via down-regulating swiprosin-1." dans: Acta pharmacologica Sinica, Vol. 38, Issue 7, pp. 1009-1023, (2018) (PubMed).
: "Retrotransposon insertions in the clonal evolution of pancreatic ductal adenocarcinoma." dans: Nature medicine, Vol. 21, Issue 9, pp. 1060-4, (2015) (PubMed).
: "Expression of SIRT1 and apoptosis-related proteins is predictive for lymph node metastasis and disease-free survival in luminal A breast cancer." dans: Virchows Archiv : an international journal of pathology, Vol. 467, Issue 5, pp. 563-70, (2015) (PubMed).
: "Human interleukin 23 receptor induces cell apoptosis in mammalian cells by intrinsic mitochondrial pathway associated with the down-regulation of RAS/mitogen-activated protein kinase and signal ..." dans: International journal of molecular sciences, Vol. 14, Issue 12, pp. 24656-69, (2014) (PubMed).
: "[Intralobar sequestration in elderly patient, report of a case]" dans: Kyobu geka. The Japanese journal of thoracic surgery, Vol. 61, Issue 9, pp. 812-5, (2008) (PubMed).
: "Calcium blocks formation of apoptosome by preventing nucleotide exchange in Apaf-1." dans: Molecular cell, Vol. 25, Issue 2, pp. 181-92, (2007) (PubMed).
: "Mechanical aspects of apoptosome assembly." dans: Current opinion in cell biology, Vol. 18, Issue 6, pp. 677-84, (2006) (PubMed).
Synonymes et noms alternatifs relatifs à APAF1
Death-associated APAF1-related killer (Dark), apoptotic peptidase activating factor 1 L homeolog (apaf1.L), apoptotic peptidase activating factor 1 (apaf1), apoptotic peptidase activating factor 1 (APAF1), apoptotic peptidase activating factor 1 (Apaf1), 6230400I06Rik, anon-53Fa, Apaf-1, apaf-1, APAF-1, APAF1, Apaf1, apaf1, Apaf1l, arc, ARK, ark, CED4, CG6829, D-Apaf-1, dapaf, Dapaf-1, dAPAF-1, dApaf-1, dapaf-1, dApaf-1/DARK/HAC-1, Dapaf-1/HAC-1, dapaf-1L, dapaf-1S, dApaf1, DARK, Dark, dArk, dark, Dark/Apaf-I, dark/dapaf-1/hac-1, Dark/Dapaf-1/HAC1, Dark/Hac-1/dApaf-1, dark/hac-1/dapaf-1, Dark/Hac-1/dApaf1, Dmel\\CG6829, fog, Hac-1, hac-1, Hac-1/Dark, Hac1, hac1, l(2)SH0173, mKIAA0413, T1, zgc:136543Protein level used designations for APAF1
- Apaf-1 related
- Apaf-1 related killer
- Apaf-1-related killer
- Ark-PA
- Ark-PB
- CG6829-PA
- CG6829-PB
- apaf1-related killer
- dark
- drosophila Apaf-1-related killer
- lethal (2) SH0173
- transcription unit 1
- apoptotic peptidase activating factor 1
- apoptotic protease-activating factor 1-like
- apoptotic protease-activating factor 1
- apoptotic protease activating factor 1
- forebrain overgrowth
- apaf-1
Vous êtes ici:
