APH1A Anticorps

Area-Gomez, de Groof, Boldogh, Bird, Gibson, Koehler, Yu, Duff, Yaffe, Pon, Schon: "Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondria." dans: The American journal of pathology, Vol. 175, Issue 5, pp. 1810-6, (2009) (PubMed).

Spasic, Raemaekers, Dillen, Declerck, Baert, Serneels, Füllekrug, Annaert: "Rer1p competes with APH-1 for binding to nicastrin and regulates gamma-secretase complex assembly in the early secretory pathway." dans: The Journal of cell biology, Vol. 176, Issue 5, pp. 629-40, (2007) (PubMed).

Ma, Li, Price, Wong: "APH-1a is the principal mammalian APH-1 isoform present in gamma-secretase complexes during embryonic development." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 25, Issue 1, pp. 192-8, (2005) (PubMed).

Periz, Fortini: "Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2." dans: Journal of neuroscience research, Vol. 77, Issue 3, pp. 309-22, (2004) (PubMed).

Takasugi, Tomita, Hayashi, Tsuruoka, Niimura, Takahashi, Thinakaran, Iwatsubo: "The role of presenilin cofactors in the gamma-secretase complex." dans: Nature, Vol. 422, Issue 6930, pp. 438-41, (2003) (PubMed).

Marlow, Canet, Haugabook, Hardy, Lahiri, Sambamurti: "APH1, PEN2, and Nicastrin increase Abeta levels and gamma-secretase activity." dans: Biochemical and biophysical research communications, Vol. 305, Issue 3, pp. 502-9, (2003) (PubMed).

Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." dans: Genome research, Vol. 13, Issue 10, pp. 2265-70, (2003) (PubMed).

Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." dans: Nature genetics, Vol. 36, Issue 1, pp. 40-5, (2003) (PubMed).

Gu, Chen, Sanjo, Kawarai, Hasegawa, Duthie, Li, Ruan, Luthra, Mount, Tandon, Fraser, St George-Hyslop: "APH-1 interacts with mature and immature forms of presenilins and nicastrin and may play a role in maturation of presenilin.nicastrin complexes." dans: The Journal of biological chemistry, Vol. 278, Issue 9, pp. 7374-80, (2003) (PubMed).

Goutte, Tsunozaki, Hale, Priess: "APH-1 is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 2, pp. 775-9, (2002) (PubMed).