ASL Produits
(Argininosuccinate Lyase (ASL))
Catégories
This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
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Catégories ASL en vedette
ASL Anticorps
High quality antibodies with extensive validation data.
ASL Kits ELISA
Reliable ELISA kits for a wide range of species.
ASL Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ASL recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (1)
- (6)
N° du produit
ABIN2856924
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
N° du produit
ABIN6137201
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
N° du produit
ABIN7144595
Quantité
100 μg
Fiche technique
Fiche technique
ASL recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Validations
N° du produit
ABIN1122449
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1122450
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Validations
N° du produit
ABIN1122451
Quantité
96 tests
Fiche technique
Fiche technique
ASL recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1345857
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7121890
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN3127494
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits ASL
: "Argininosuccinate lyase interacts with cyclin A2 in cytoplasm and modulates growth of liver tumor cells." dans: Oncology reports, Vol. 37, Issue 2, pp. 969-978, (2017) (PubMed).: "Argininosuccinate lyase is a potential therapeutic target in breast cancer." dans: Oncology reports, Vol. 34, Issue 6, pp. 3131-9, (2015) (PubMed).
: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." dans: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).
: "Epigenetic status of argininosuccinate synthetase and argininosuccinate lyase modulates autophagy and cell death in glioblastoma." dans: Cell death & disease, Vol. 4, pp. e458, (2013) (PubMed).
: "Understanding the role of argininosuccinate lyase transcript variants in the clinical and biochemical variability of the urea cycle disorder argininosuccinic aciduria." dans: The Journal of biological chemistry, Vol. 288, Issue 48, pp. 34599-611, (2013) (PubMed).
: "Argininosuccinate lyase deficiency: mutational spectrum in Italian patients and identification of a novel ASL pseudogene." dans: Human mutation, Vol. 28, Issue 7, pp. 694-702, (2007) (PubMed).
: "A novel stop codon mutation (X465Y) in the argininosuccinate lyase gene in a patient with argininosuccinic aciduria." dans: The Tohoku journal of experimental medicine, Vol. 198, Issue 2, pp. 119-24, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à ASL
argininosuccinate lyase (ASL), argininosuccinate lyase (Asl), argininosuccinate lyase (asl), argininosuccinate lyase (argH2), argininosuccinate lyase ArgH (argH), argininosuccinate lyase (argH), argininosuccinate lyase (arg7), argininosuccinate lyase (CNC04420), argininosuccinate lyase (STHERM_c13370), adenylosuccinate lyase (Adsl), argininosuccinate lyase L homeolog (asl.L), argininosuccinate lyase (ARG7), 2510006M18Rik, Adl, ASAL, Asl, BA4879, PSPTO0125, zgc:63532Protein level used designations for ASL
- argininosuccinase
- arginosuccinase
- ASAL
- argininosuccinate lyase
- ASase
- adenylosuccinase
- adenylosuccinate lyase 1
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