ATF6 Produits
(Activating Transcription Factor 6 (ATF6))
Catégories
This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer, and following ER stress-induced proteolysis, it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells. There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations, but another polymorphism has been associated with increased plasma cholesterol levels. This gene is also thought to be a potential therapeutic target for cystic fibrosis. [provided by RefSeq, Aug 2011].
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Catégories ATF6 en vedette
ATF6 Anticorps
High quality antibodies with extensive validation data.
ATF6 Kits ELISA
Reliable ELISA kits for a wide range of species.
ATF6 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ATF6 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (3)
- (9)
N° du produit
ABIN1512605
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (5)
N° du produit
ABIN7440587
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (1)
- (4)
N° du produit
ABIN652625
Quantité
400 μL
Fiche technique
Fiche technique
ATF6 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6964572
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6964573
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6962051
Quantité
96 tests
Fiche technique
Fiche technique
ATF6 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7121670
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1345942
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1345944
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits ATF6
: "Ebola Virus Activates IRE1α-Dependent XBP1u Splicing." dans: Viruses, Vol. 15, Issue 1, (2023) (PubMed).: "Counteracting Cisplatin-Induced Testicular Damages by Natural Polyphenol Constituent Honokiol." dans: Antioxidants (Basel, Switzerland), Vol. 9, Issue 8, (2020) (PubMed).
: "Loss of Calreticulin Uncovers a Critical Role for Calcium in Regulating Cellular Lipid Homeostasis." dans: Scientific reports, Vol. 7, Issue 1, pp. 5941, (2019) (PubMed).
: "EMC3 coordinates surfactant protein and lipid homeostasis required for respiration." dans: The Journal of clinical investigation, Vol. 127, Issue 12, pp. 4314-4325, (2019) (PubMed).
: "Expressions of ATF6, XBP1, and GRP78 in normal tissue, atypical adenomatous hyperplasia, and adenocarcinoma of the lung." dans: Human pathology, Vol. 83, pp. 22-28, (2019) (PubMed).
: "IL-6 mediates ER expansion during hyperpolarization of alternatively activated macrophages." dans: Immunology and cell biology, Vol. 97, Issue 2, pp. 203-217, (2019) (PubMed).
: "Imatinib‑induced apoptosis of gastric cancer cells is mediated by endoplasmic reticulum stress." dans: Oncology reports, Vol. 41, Issue 3, pp. 1616-1626, (2019) (PubMed).
: "The effect of Tmem135 overexpression on the mouse heart." dans: PLoS ONE, Vol. 13, Issue 8, pp. e0201986, (2019) (PubMed).
: "Tauroursodeoxycholic acid attenuates cyclosporine-induced renal fibrogenesis in the mouse model." dans: Biochimica et biophysica acta. General subjects, Vol. 1863, Issue 7, pp. 1210-1216, (2019) (PubMed).
: "C/EBPβ mediates palmitate-induced musclin expression via the regulation of PERK/ATF4 pathways in myotubes." dans: American journal of physiology. Endocrinology and metabolism, Vol. 316, Issue 6, pp. E1081-E1092, (2019) (PubMed).
Synonymes et noms alternatifs relatifs à ATF6
activating transcription factor 6 (ATF6), uncharacterized LOC412432 (LOC412432), activating transcription factor 6 S homeolog (atf6.S), cyclic AMP-dependent transcription factor ATF-6 alpha (LOC100122162), activating transcription factor 6 (Atf6), 9130025P16Rik, 9630036G24, AA789574, ATF-6-like, ATF6, Atf6, ATF6A, Atf6alpha, ESTM49, GB16435Protein level used designations for ATF6
- activating transcription factor 6
- cyclic AMP-dependent transcription factor ATF-6 alpha-like
- cAMP-dependent transcription factor ATF-6 alpha
- cyclic AMP-dependent transcription factor ATF-6 alpha
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