ATIC Produits
(5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC))
Catégories
This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq, Sep 2009].
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Catégories ATIC en vedette
ATIC Anticorps
High quality antibodies with extensive validation data.
ATIC Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ATIC recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (4)
N° du produit
ABIN7145576
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (3)
N° du produit
ABIN2855541
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN6260111
Quantité
100 μL
Fiche technique
Fiche technique
ATIC recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6226403
Quantité
96 tests
Fiche technique
Fiche technique
ATIC recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1345986
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3086774
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3128527
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits ATIC
: "Mass spectrometric/bioinformatic identification of a protein subset that characterizes the cellular activity of anticancer peptides." dans: Journal of proteome research, Vol. 13, Issue 11, pp. 5250-61, (2014) (PubMed).: "5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase." dans: The Journal of biological chemistry, Vol. 280, Issue 47, pp. 39582-93, (2005) (PubMed).
: "AICA-ribosiduria: a novel, neurologically devastating inborn error of purine biosynthesis caused by mutation of ATIC." dans: American journal of human genetics, Vol. 74, Issue 6, pp. 1276-81, (2004) (PubMed).
: "The kinetic mechanism of the human bifunctional enzyme ATIC (5-amino-4-imidazolecarboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase). A surprising lack of substrate ..." dans: The Journal of biological chemistry, Vol. 277, Issue 25, pp. 22168-74, (2002) (PubMed).
Synonymes et noms alternatifs relatifs à ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase L homeolog (atic.L), bifunctional purine biosynthesis protein PurH (purH), bifunctional purine biosynthesis protein purH (purH), Bifunctional purine biosynthesis protein purH (purH), Bifunctional purine biosynthesis protein PurH (purH), 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC), 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (Atic), 2610509C24Rik, AA536954, AICAR, AICARFT, AW212393, IMPCHASE, PURH, purHProtein level used designations for ATIC
- bifunctional purine biosynthesis protein PurH
- bifunctional purine biosynthesis protein purH
- Bifunctional purine biosynthesis protein purH
- Bifunctional purine biosynthesis protein PurH
- 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotide transformylase/inosinicase
- AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme
- AICARFT/IMPCHASE
- bifunctional purine biosynthesis protein PURH
- phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
- 5-aminoimidazole-4-carboxamide-ribonucleotide transformylase-IMP cyclohydrolase, ATIC
- aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase
- aminoimidazole-4-carboxamide ribonucleotidetransformylase/IMP cyclohydrolase
- bifunctional purine biosynthesis protein
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- ATG4C
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- ATG4-2
- ATG3
- ATG2B
- ATG2A
- ATG29
- ATG19
- ATG16L2
- ATG16L1
- ATG14
- ATG13
- ATL1
- ATL2
- ATL3
- Atlastin-2
- ATM
- ATM Interactor
- ATOH1
- ATOH8
- Atonal Homolog 7
- ATOX1
- ATP Synthase Subunit beta
- ATP Synthase Subunit gamma
- ATP Synthase, H+ Transporting, Mitochondrial F0 Complex, Subunit E
- ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1A
- ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B
- ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4
- ATP-Binding Cassette, Sub-Family D (Ald), Member 3
- ATP-Binding Protein p29
- ATP-Dependent Clp Protease Proteolytic Subunit 3
- ATP10
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