ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Produits
(ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B))
Catégories
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq, Jul 2008].
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Catégories ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B en vedette
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Anticorps
High quality antibodies with extensive validation data.
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
ELISA, WB, FACS, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
- (4)
- (4)
N° du produit
ABIN670161
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
ELISA, WB, FACS, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
- (1)
N° du produit
ABIN686977
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Plasmodium falciparum
Application
ELISA
Validations
N° du produit
ABIN7178310
Quantité
100 μg
Fiche technique
Fiche technique
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN3132561
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN3132562
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3132560
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B
: "The impact of insulin on chemotherapeutic sensitivity to 5-fluorouracil in gastric cancer cell lines SGC7901, MKN45 and MKN28." dans: Journal of experimental & clinical cancer research : CR, Vol. 34, pp. 64, (2016) (PubMed).: "MicroRNA-186 induces sensitivity of ovarian cancer cells to paclitaxel and cisplatin by targeting ABCB1." dans: Journal of ovarian research, Vol. 8, pp. 80, (2016) (PubMed).
: "Chronic inflammation up-regulates P-gp in peripheral mononuclear blood cells via the STAT3/Nf-κb pathway in 2,4,6-trinitrobenzene sulfonic acid-induced colitis mice." dans: Scientific reports, Vol. 5, pp. 13558, (2016) (PubMed).
: "Ascites Increases Expression/Function of Multidrug Resistance Proteins in Ovarian Cancer Cells." dans: PLoS ONE, Vol. 10, Issue 7, pp. e0131579, (2015) (PubMed).
: "Development of a novel orthotopic non-small cell lung cancer model and therapeutic benefit of 2'-(2-bromohexadecanoyl)-docetaxel conjugate nanoparticles." dans: Nanomedicine : nanotechnology, biology, and medicine, Vol. 10, Issue 7, pp. 1497-506, (2014) (PubMed).
: "The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer." dans: Journal of experimental & clinical cancer research : CR, Vol. 28, pp. 144, (2009) (PubMed).
Synonymes et noms alternatifs relatifs à ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B
ATP binding cassette subfamily B member 1 (ABCB1), ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b), ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b), ABC20, Abcb1, CD243, CLCS, GP170, mdr, MDR1, Mdr1, Mdr1b, P-GP, Pgy-1, PGY1, Pgy1Protein level used designations for ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B
- P-glycoprotein 1
- colchicin sensitivity
- doxorubicin resistance
- multidrug resistance protein 1
- ATP-binding cassette sub-family B member 1
- P glycoprotein 1
- multidrug resistance protein 1B
- ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1)
- ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1)
- ATP-binding cassette, sub-family B (MDR/TAP), member 1B
- ATP-binding cassette, subfamily B, member 1B
- P-glycoprotein/multidrug resistance 1
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