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ATP7A Produits

(ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A))
This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans-Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked cutis laxa, and occipital horn syndrome. [provided by RefSeq, Oct 2011].

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Catégories ATP7A en vedette

ATP7A Anticorps

High quality antibodies with extensive validation data.

ATP7A Kits ELISA

Reliable ELISA kits for a wide range of species.

ATP7A Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ATP7A recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, IF, ICC
Validations
  • (4)
N° du produit ABIN2485193
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, IF, ICC
Validations
  • (4)
N° du produit ABIN2485192
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, IF, ICC
Validations
  • (4)
N° du produit ABIN2485191
Quantité 100 μg
Fiche technique Fiche technique

ATP7A recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6965087
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1127849
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method
Validations
N° du produit ABIN1127850
Quantité 96 tests
Fiche technique Fiche technique

ATP7A recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1346155
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN3089625
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN3123304
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits ATP7A

Wang, Zhu, Zhao, Wang: "miR-133a enhances the sensitivity of Hep-2 cells and vincristine-resistant Hep-2v cells to cisplatin by downregulating ATP7B expression." dans: International journal of molecular medicine, Vol. 37, Issue 6, pp. 1636-42, (2016) (PubMed).

Ha, Doguer, Collins: "Knockdown of copper-transporting ATPase 1 (Atp7a) impairs iron flux in fully-differentiated rat (IEC-6) and human (Caco-2) intestinal epithelial cells." dans: Metallomics : integrated biometal science, Vol. 8, Issue 9, pp. 963-972, (2016) (PubMed).

Montero-Melendez, Gobbetti, Cooray, Jonassen, Perretti: "Biased agonism as a novel strategy to harness the proresolving properties of melanocortin receptors without eliciting melanogenic effects." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 7, pp. 3381-8, (2015) (PubMed).

White, Kambe, Fulcher, Sachdev, Bush, Fritsche, Lee, Quinn, Petris: "Copper transport into the secretory pathway is regulated by oxygen in macrophages." dans: Journal of cell science, Vol. 122, Issue Pt 9, pp. 1315-21, (2009) (PubMed).

White, Lee, Kambe, Fritsche, Petris: "A role for the ATP7A copper-transporting ATPase in macrophage bactericidal activity." dans: The Journal of biological chemistry, Vol. 284, Issue 49, pp. 33949-56, (2009) (PubMed).

Setty, Tenza, Sviderskaya, Bennett, Raposo, Marks: "Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes." dans: Nature, Vol. 454, Issue 7208, pp. 1142-6, (2008) (PubMed).

Schlief, West, Craig, Holtzman, Gitlin: "Role of the Menkes copper-transporting ATPase in NMDA receptor-mediated neuronal toxicity." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 40, pp. 14919-24, (2006) (PubMed).

Steveson, Ciccotosto, Ma, Mueller, Mains, Eipper: "Menkes protein contributes to the function of peptidylglycine alpha-amidating monooxygenase." dans: Endocrinology, Vol. 144, Issue 1, pp. 188-200, (2002) (PubMed).

Synonymes et noms alternatifs relatifs à ATP7A

ATPase copper transporting alpha (ATP7A), ATPase, Cu++ transporting, alpha polypeptide (ATP7A), ATPase, Cu++ transporting, alpha polypeptide (atp7a), P-type ATPase (atp7a), ATP synthase subunit a (LOC100049514), ATPase, Cu++ transporting, alpha polypeptide (Atp7a), ATPase copper transporting alpha (atp7a), copper-transporting ATPase 1 (LOC412379), ATPase copper transporting alpha (Atp7a), ATP7A, Atp7a, atp7a, atpase, Blo, blotchy, br, brindled, cal, DDBDRAFT_0218568, DDBDRAFT_0235190, DDB_0218568, DDB_0235190, DSMAX, DXHXS1608e, I14, kal, MK, MNK, Mnk, Mo, mottled, SMAX3, wu:fc43e01, zgc:153422, zgc:158633

Protein level used designations for ATP7A

  • ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome)
  • ATPase, Cu++ transporting, alpha polypeptide
  • Menkes disease ATPase
  • calamity
  • copper-transporting ATPase 1
  • copper-transporting P-type ATPase
  • copper-transporting ATPase
  • ATPase protein
  • kaleidoscope
  • Copper-transporting ATPase 1
  • copper-transporting ATPase 1-like
  • Cu++-transporting P-type ATPase
  • Menkes disease-associated protein
  • copper pump 1
  • Menkes protein
  • menkes disease-associated protein homolog
  • copper transporting ATPase
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