ATP7B Produits
(ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))
Catégories
This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD). [provided by RefSeq, Jul 2008].
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Catégories ATP7B en vedette
ATP7B Anticorps
High quality antibodies with extensive validation data.
ATP7B Kits ELISA
Reliable ELISA kits for a wide range of species.
ATP7B Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ATP7B recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (8)
N° du produit
ABIN7441340
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IF, IHC (p), FACS
Validations
- (7)
N° du produit
ABIN390398
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (3)
N° du produit
ABIN560009
Quantité
100 μg
Fiche technique
Fiche technique
ATP7B recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6953997
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6953998
Quantité
96 tests
Fiche technique
Fiche technique
ATP7B recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1346157
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN3089679
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN3123315
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits ATP7B
: "PAMAM dendrimer grafted cellulose paper scaffolds as a novel in vitro 3D liver model for drug screening applications." dans: Colloids and surfaces. B, Biointerfaces, Vol. 172, pp. 346-354, (2019) (PubMed).: "The release and detection of copper ions from ultrasmall theranostic Cu2-xSe nanoparticles." dans: Nanoscale, Vol. 11, Issue 24, pp. 11819-11829, (2019) (PubMed).
: "Rational Targeting of Cdc42 Overcomes Drug Resistance of Multiple Myeloma." dans: Frontiers in oncology, Vol. 9, pp. 958, (2019) (PubMed).
: "The loss of copper is associated with the increase in copper metabolism MURR domain 1 in ischemic hearts of mice." dans: Experimental biology and medicine (Maywood, N.J.), Vol. 243, Issue 9, pp. 780-785, (2018) (PubMed).
: "A Modular Ionophore Platform for Liver-Directed Copper Supplementation in Cells and Animals." dans: Journal of the American Chemical Society, (2018) (PubMed).
: "miR-133a enhances the sensitivity of Hep-2 cells and vincristine-resistant Hep-2v cells to cisplatin by downregulating ATP7B expression." dans: International journal of molecular medicine, Vol. 37, Issue 6, pp. 1636-42, (2016) (PubMed).
: "A Chinese herbal Formula, Chang-Wei-Qin, Synergistically Enhances Antitumor Effect of Oxaliplatin." dans: Pathology oncology research : POR, Vol. 21, Issue 2, pp. 389-97, (2015) (PubMed).
: "Mechanistic basis of a combination D-penicillamine and platinum drugs synergistically inhibits tumor growth in oxaliplatin-resistant human cervical cancer cells in vitro and in vivo." dans: Biochemical pharmacology, Vol. 95, Issue 1, pp. 28-37, (2015) (PubMed).
: "Novel ATPase Cu(2+) transporting beta polypeptide mutations in Chinese families with Wilson's disease." dans: PLoS ONE, Vol. 8, Issue 7, pp. e66526, (2013) (PubMed).
: "Is ATP7B a predictive marker in patients with ovarian carcinoma treated with platinum-taxane combination chemotherapy?" dans: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, Vol. 23, Issue 1, pp. 60-4, (2012) (PubMed).
Synonymes et noms alternatifs relatifs à ATP7B
ATPase copper transporting beta (ATP7B), ATPase, Cu++ transporting, beta polypeptide (Atp7b), ATPase copper transporting beta (Atp7b), ATPase, Cu++ transporting, beta polypeptide (Wilson disease) (atp7b), copper-transporting ATPase 2 (LOC592143), ATPase, Cu++ transporting, beta polypeptide (atp7b), ATPase copper transporting beta (atp7b), Atp7a, ATP7B, Hts, PINA, PWD, tx, WC1, WD, Wd, WNDProtein level used designations for ATP7B
- ATPase, Cu(2+)- transporting, beta polypeptide
- Wilson disease-associated protein
- copper pump 2
- copper-transporting ATPase 2
- Wilson protein
- toxic milk
- wilson disease-associated protein homolog
- ATPase, Cu++ transporting, beta polypeptide (same as Wilson disease)
- PINA gene, promoter
- pineal night-specific ATPase
- ATPase 7B protein
- ATPase, Cu++ transporting, beta polypeptide (Wilson disease)
- Wilson's disease protein
- copper-transporting ATPase
- ATPase, Cu++ transporting, beta polypeptide
- ATP7B-like
- ATPase, Cu(2+)-transporting, beta polypeptide
- copper-transporting ATPase 2-like
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