AXL Produits
(AXL Receptor tyrosine Kinase (AXL))
Catégories
The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
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Catégories AXL en vedette
AXL Anticorps
High quality antibodies with extensive validation data.
AXL Kits ELISA
Reliable ELISA kits for a wide range of species.
AXL Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
AXL recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, RNAi
Validations
- (1)
- (6)
N° du produit
ABIN560017
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, IF
Validations
- (5)
N° du produit
ABIN7265804
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
- (4)
N° du produit
ABIN7265803
Quantité
100 μL
Fiche technique
Fiche technique
AXL recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6954023
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6954024
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN625112
Quantité
96 tests
Fiche technique
Fiche technique
AXL recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (5)
N° du produit
ABIN7273881
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (5)
N° du produit
ABIN7273880
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN7273884
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits AXL
: "Deficiency of Axl aggravates pulmonary arterial hypertension via BMPR2. ..." dans: Communications biology, Vol. 4, Issue 1, pp. 1002, (2021) (PubMed).: "Hematopoietic niche drives FLT3-ITD acute myeloid leukemia resistance to quizartinib via STAT5- and hypoxia- dependent up-regulation of AXL. ..." dans: Haematologica, (2019) (PubMed).
: "Characterization of the Filovirus-Resistant Cell Line SH-SY5Y Reveals Redundant Role of Cell Surface Entry Factors." dans: Viruses, Vol. 11, Issue 3, (2019) (PubMed).
: "Pan-TAM Tyrosine Kinase Inhibitor BMS-777607 Enhances Anti-PD-1 mAb Efficacy in a Murine Model of Triple-Negative Breast Cancer." dans: Cancer research, Vol. 79, Issue 10, pp. 2669-2683, (2019) (PubMed).
: "Inhibition of MERTK Promotes Suppression of Tumor Growth in BRAF Mutant and BRAF Wild-Type Melanoma." dans: Molecular cancer therapeutics, Vol. 18, Issue 2, pp. 278-288, (2019) (PubMed).
: "p5RHH nanoparticle-mediated delivery of AXL siRNA inhibits metastasis of ovarian and uterine cancer cells in mouse xenografts." dans: Scientific reports, Vol. 9, Issue 1, pp. 4762, (2019) (PubMed).
: "Csf1r or Mer inhibition delays liver regeneration via suppression of Kupffer cells." dans: PLoS ONE, Vol. 14, Issue 5, pp. e0216275, (2019) (PubMed).
: "Lipopolysaccharide inhalation recruits monocytes and dendritic cell subsets to the alveolar airspace." dans: Nature communications, Vol. 10, Issue 1, pp. 1999, (2019) (PubMed).
: "Axl Promotes Zika Virus Entry and Modulates the Antiviral State of Human Sertoli Cells." dans: mBio, Vol. 10, Issue 4, (2019) (PubMed).
: "Platelets Promote Macrophage Polarization toward Pro-inflammatory Phenotype and Increase Survival of Septic Mice." dans: Cell reports, Vol. 28, Issue 4, pp. 896-908.e5, (2019) (PubMed).
Synonymes et noms alternatifs relatifs à AXL
AXL receptor tyrosine kinase (AXL), AXL receptor tyrosine kinase (Axl), Axl receptor tyrosine kinase (Axl), AI323647, Ark, JTK11, Tyro7, UFO, UfoProtein level used designations for AXL
- AXL oncogene
- AXL transforming sequence/gene
- tyrosine-protein kinase receptor UFO
- adhesion-related kinase
- ufo oncogene homolog
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